Granted Patent
B2
US 9,688,733 · App. 14/436,920 · Granted Jun 27, 2017
Method for treating spinal cord injury using HMGB1 fragment
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Abstract
Fragment peptides having a proper length, which consists of a portion of the HMGB1 protein were synthesized, and the peptides were confirmed to show therapeutic effects on injury of the spinal cord.
Claims (2)
1. A method for treating injury or the spinal cord, comprising the step of administering a peptide that has an activity of stimulating the migration of mesenchymal stem cells, and comprises an amino acid sequence selected from the group consisting of SEQ ID NO: 3, SEQ ID NO: 4, and SEQ ID NO: 5.
2. A method for treating injury of the spinal cord, comprising the step of administering a peptide consisting of an amino acid sequence selected from the group consisting of SEQ ID NO: 3, SEQ ID NO: 4, and SEQ ID NO: 5.
Assignments (3)
CHANGE OF NAME
Recorded Sep 18, 2018
From: GENOMIX CO., LTD.
To: STEMRIM INC.
Reel/Frame 047102/0685 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Aug 13, 2015
From: YAMAZAKI, TAKEHIKO; CUI, WENHAO
To: GENOMIX CO., LTD.
Reel/Frame 036320/0356 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Aug 13, 2015
From: TAMAI, KATSUTO
To: OSAKA UNIVERSITY
Reel/Frame 036320/0380 →
Priority Claims (1)
JP 2012-235786
· Oct 25, 2012
· national
Continuity (1)