Metabolism-improving agent comprising rare fatty acid
The present invention provides a metabolism improving agent comprising an oxo fatty acid having 18 carbon atoms and a carbonyl group at the 10- or 12-position, and/or a hydroxy fatty acid having 18 carbon atoms and a hydroxyl group at the 10- and/or 12-position(s), and use of the metabolism improving agent as a food, a pharmaceutical product and the like.
1. A method of improving metabolism in a mammal, comprising administering an oxo fatty acid having 18 carbon atoms and a carbonyl group at the 10-position, and/or a hydroxy fatty acid having 18 carbon atoms and a hydroxyl group at the 10-position, or an agent comprising the same to the mammal.
2. The method according to claim 1 , wherein the aforementioned oxo fatty acid and/or hydroxy fatty acid have/has a trans double bond at the 11-position, or a cis double bond at the 12-position.
3. The method according to claim 2 , which is used for the improvement of at least one kind selected from the group consisting of obesity, diabetes, lipid metabolism abnormality, hyperlipidemia, and fatty liver.
4. The method according to claim 2 , wherein the agent is a food or a food additive.
5. The method according to claim 2 , wherein the agent is a pharmaceutical product.
6. The method according to claim 2 , wherein the agent is a feed or a feed additive.
7. The method according to claim 1 , wherein the oxo fatty acid is at least one kind selected from the group consisting of 10-oxo-cis-12-octadecenoic acid, 10-oxo-cis-12,cis-15-octadecadienoic acid, 10-oxo-cis-6,cis-12-octadecadienoic acid, 10-oxo-cis-6,cis-12,cis-15-octadecatrienoic acid, 10-oxooctadecanoic acid, 10-oxo-cis-6-octadecenoic acid, 10-oxo-cis-15-octadecenoic acid, 10-oxo-cis-6,cis-15-octadecadienoic acid, 10-oxo-trans-11-octadecenoic acid, 10-oxo-cis-6,trans-11-octadecadienoic acid, 10-oxo-trans-11,cis-15-octadecadienoic acid, and 10-oxo-cis-6,trans-11,cis-15-octadecatrienoic acid.
8. The method according to claim 7 , which is used for the improvement of at least one kind selected from the group consisting of obesity, diabetes, lipid metabolism abnormality, hyperlipidemia, and fatty liver.
9. The method according to claim 7 , wherein the agent is a food or a food additive.
10. The method according to claim 7 , wherein the agent is a pharmaceutical product.
11. The method according to claim 7 , wherein the agent is a feed or a feed additive.
12. The method according to claim 1 , wherein the hydroxy fatty acid is at least one kind selected from the group consisting of 10-hydroxy-cis-12-octadecenoic acid, 10-hydroxy-cis-12,cis-15-octadecadienoic acid, 10-hydroxy-cis-6,cis-12-octadecadienoic acid, 10-hydroxy-cis-6,cis-12,cis-15-octadecatrienoic acid, 10-hydroxyoctadecanoic acid, 10-hydroxy-cis-15-octadecenoic acid, 10-hydroxy-cis-6-octadecenoic acid, 10-hydroxy-cis-6,cis-15-octadecadienoic acid, 10-hydroxy-trans-11-octadecenoic acid, 10-hydroxy-trans-11,cis-15-octadecadienoic acid, 10-hydroxy-cis-6,trans-11-octadecadienoic acid, and 10-hydroxy-cis-6,trans-11,cis-15-octadecatrienoic acid.
13. The method according to claim 12 , which is used for the improvement of at least one kind selected from the group consisting of obesity, diabetes, lipid metabolism abnormality, hyperlipidemia, and fatty liver.
14. The method according to claim 12 , wherein the agent is a food or a food additive.
15. The method according to claim 12 , wherein the agent is a pharmaceutical product.
16. The method according to claim 12 , wherein the agent is a feed or a feed additive.
17. The method according to claim 1 , which is used for the improvement of at least one kind selected from the group consisting of obesity, diabetes, lipid metabolism abnormality, hyperlipidemia, and fatty liver.
18. The method according to claim 1 , wherein the agent is a food or a food additive.
19. The method according to claim 1 , wherein the agent is a pharmaceutical product.
20. The method according to claim 1 , wherein the agent is a feed or a feed additive.