IP Library Granted Patent US 9,585,910
Granted Patent B2
US 9,585,910 · App. 14/445,744 · Granted Mar 7, 2017

Polymers functionalized with ion-specific recognition elements

Inventors: Jonathan L. Sessler (Austin, TX); Christopher W. Bielawski (Austin, TX); Abdullah Aydogan (Austin, TX); Daniel J. Coady (Austin, TX)
Assignee: Board of Regents, The University of Texas System
A61K31/787A61K31/74B01D15/00B01J20/26B01J20/261B01J20/262B01J20/265B01J20/321B01J20/3212B01J20/3255B01J41/125B01J45/00A61K47/48076A61K51/1241A61K51/1268
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Quick Facts
Patent No.
US 9,585,910
App. No.
14/445,744
Granted
Mar 7, 2017
Kind
B2
Abstract

Polymeric compounds containing polymer backbones functionalized with ion-specific recognition elements and methods for the use of these compounds are described herein. The polymeric compounds may contain multiple types of ion-specific recognition elements depending on a specific application. The polymeric compounds can be used to remove ionic species from a solution, for example, in separations applications in which a single or multiple types of ionic species are desired to be removed from the solution.

Claims (4)

1. A method of treating an ion imbalance in a subject comprising:

selecting a subject having an elevated level of an ion; and

administering to the subject a block copolymer comprising multiple repeating units, wherein at least one block is uniformly formed from repeating units covalently bound to a calix[4]pyrrole and wherein at least one block is uniformly formed from repeating units covalently bound to a crown ether, and wherein the multiple repeating units are selected from the group consisting of polyacryonitrile, polyacrylate, polystyrene, polyester, polyurethane, polyamide, and a co-polymer thereof.

2. The method of claim 1 , wherein the crown ether is a benzo-15-crown-5 ether.

Assignments (3)
CONFIRMATORY LICENSE Recorded Jun 3, 2015
From: UNIVERSITY OF TEXAS, AUSTIN
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 035813/0613 →
ASSIGNMENT TO REPLACE INCORRECT ASSIGNMENT RECORDED UNDER REEL 033555 AND FRAME 0384 Recorded Sep 4, 2014
From: SESSLER, JONATHAN L.; BIELAWSKI, CHRISTOPHER W.; AYDOGAN, ABDULLAH; COADY, DANIEL J.
To: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
Reel/Frame 033686/0862 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 18, 2014
From: SESSLER, JONATHAN L.; BIELAWSKI, CHRISTOPHER W.; AYDOGAN, ABDULLAH; COADY, DANIEL J.
To: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
Reel/Frame 033555/0384 →
Continuity (3)
Continuation 12623943 · Nov 23, 2009
Provisional Application 61118170 · Nov 26, 2008
Related Publication 20150086501A1 · Mar 26, 2015