Antiviral agent against animal viruses
Provided is an antiviral agent against animal viruses. The antiviral agent contains a protein or a nucleic acid sequence encoding the protein, as an active ingredient, the protein having binding ability and degrading ability to foreign nucleic acid chains invaded in an animal cell and that has no cytotoxicity to the animal cell itself. Also provided is an antiviral animal cell containing the protein according to the present invention, or the nucleic acid sequence encoding the protein. The antiviral agent and antiviral animal cell exhibit advantageous effects in that they selectively degrade foreign nucleic acid chains invaded in an animal cell and have no cytotoxicity to the animal cell, thus causing no death of the animal cell.
1. A method of inhibiting an RNA virus comprising contacting said RNA virus with a composition comprising a single-chain variable fragment (scFv) consisting of the sequence set forth in SEQ ID NO: 6, wherein said composition degrades RNA of said RNA virus thereby inhibiting said RNA virus.
2. The method of claim 1 , wherein said RNA comprises positive (+) sense single stranded (ss) RNA, negative (−) sense ss RNA, or double stranded (ds) RNA.