ANTIVIRAL PHARMACEUTICAL FOR TOPICAL ADMINISTRATION
An enzymatically-active ribonuclease is combined with a vehicle that does not unacceptably interfere with such enzymatic activity and applied externally. Advantageously, the ribonuclease is ranpirnase. The vehicle can be a liquid, a gel, an ointment, or a serum, and can also be an approved sexual lubricant.
1 . A pharmaceutical comprising a therapeutically effective quantity of an enzymatically-active ribonuclease and a vehicle that does not unacceptably interfere with such enzymatic activity.
2 . The pharmaceutical of claim 1 , wherein the enzymatically-active ribonuclease is ranpirnase.
3 . The pharmaceutical of claim 1 , wherein the vehicle is an aqueous vehicle.
4 . The pharmaceutical of claim 3 , wherein the vehicle is a gel, a serum, or a lotion.
5 . The pharmaceutical of claim 3 , wherein the vehicle is an approved sexual lubricant.
6 . The pharmaceutical of claim 1 , wherein the vehicle is compatible with latex condoms.
7 . The pharmaceutical of claim 2 , wherein the pharmaceutical contains between 1 and 3 mg of ranpirnase per ml of vehicle.