IP Library Granted Patent US 9,078,905
Granted Patent B2
US 9,078,905 · App. 14/490,221 · Granted Jul 14, 2015

Bioeffective krill oil compositions

Inventors: Inge Bruheim (Volda, NO); Snorre Tilseth (Bergen, NO); Daniele Mancinelli (Orsta, NO)
Assignee: AKER BIOMARINE ANTARCTIC AS
A61K35/612A61K9/4858A61K31/122A61K31/202A61K31/23A61K31/683A61K31/685A61K45/06C11B3/006
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Quick Facts
Patent No.
US 9,078,905
App. No.
14/490,221
Granted
Jul 14, 2015
Kind
B2
Abstract

This invention discloses new krill oil compositions characterized by having high amounts of phospholipids, astaxanthin esters and/or omega-3 contents. The krill oils are obtained from krill meal using supercritical fluid extraction in a two stage process. Stage 1 removes the neutral lipid by extracting with neat supercritical CO 2 or CO 2 plus approximately 5% of a co-solvent. Stage 2 extracts the actual krill oils by using supercritical CO 2 in combination with approximately 20% ethanol. The krill oil materials obtained are compared with commercially available krill oil and found to be more bioeffective in a number of areas such as anti-inflammation, anti-oxidant effects, improving insulin resistances and improving blood lipid profile.

Claims (23)

1. Encapsulated krill oil comprising:

a capsule containing an effective amount of krill oil, said krill oil comprising from about 3% to about 15% w/w ether phospholipids.

2. The encapsulated krill oil of claim 1 , wherein said krill oil comprises at least 30% total phospholipids w/w.

3. The encapsulated krill oil of claim 1 , wherein said krill oil comprises at least 30% phosphatidylcholine w/w.

4. The encapsulated krill oil of claim 1 , wherein said krill oil is a polar solvent extract of krill.

5. The encapsulated krill oil of claim 1 , wherein said capsule contains a phytonutrient derived from a source other than krill.

6. The encapsulated krill oil of claim 1 , wherein said krill oil further comprises from about 3% to about 10% w/w ether phospholipids; from about 27% to 50% w/w non-ether phospholipids so that the amount of total phospholipids in the composition is from about 30% to 60% w/w; and from about 20% to 50% w/w triglycerides.

7. The encapsulated krill oil of claim 6 , wherein said krill oil further comprises from about 20% to 35% omega-3 fatty acids as a percentage of total fatty acids in said composition.

8. The encapsulated krill oil of claim 7 , wherein from about 70% to 95% of said omega-3 fatty acids are attached to said phospholipids.

9. The encapsulated krill oil of claim 1 , wherein said krill is Euphausia superba.

10. The encapsulated krill oil of claim 1 , wherein said capsule is a soft gel capsule.

11. The encapsulated krill oil of claim 1 , wherein said krill oil comprises less than about 0.45% w/w arachadonic acid.

12. Encapsulated krill oil comprising:

a capsule containing an effective amount of krill oil, said krill oil comprising from about 3% to about 10% w/w ether phospholipids; from about 27% to 50% w/w non-ether phospholipids so that the amount of total phospholipids in the composition is from about 30% to 60% w/w; and from about 20% to 50% w/w triglycerides.

13. The encapsulated krill oil of claim 6 , wherein said krill oil further comprises from about 20% to 35% omega-3 fatty acids as a percentage of total fatty acids in said composition.

14. The encapsulated krill oil of claim 13 , wherein from about 70% to 95% of said omega-3 fatty acids are attached to said phospholipids.

15. The encapsulated krill oil of claim 12 , wherein said krill is Euphausia superba.

16. The encapsulated krill oil of claim 12 , wherein said capsule is a soft gel capsule.

17. The encapsulated krill oil of claim 12 , wherein said krill oil comprises less than about 0.45% w/w arachadonic acid.

18. Encapsulated Antarctic krill oil comprising:

a soft gel capsule containing an effective amount of krill oil, said krill oil comprising from about 3% to about 10% w/w ether phospholipids, from about 27% to 50% w/w non-ether phospholipids so that the amount of total phospholipids in the composition is from about 30% to 60% w/w; and from about 20% to 50% w/w triglycerides.

19. The encapsulated krill oil of claim 18 , wherein said krill oil further comprises from about 20% to 35% omega-3 fatty acids as a percentage of total fatty acids in said composition.

20. The encapsulated krill oil of claim 19 , wherein from about 70% to 95% of said omega-3 fatty acids are attached to said phospholipids.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 16, 2015
From: AKER BIOMARINE AS
To: AKER BIOMARINE ANTARCTIC AS
Reel/Frame 034734/0841 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 28, 2014
From: BRUHEIM, INGE; TILSETH, SNORRE; MANCINELLI, DANIELE
To: AKER BIOMARINE AS
Reel/Frame 034048/0733 →
Continuity (6)
Continuation 12057775 · Mar 28, 2008
Provisional Application 60920483 · Mar 28, 2007
Provisional Application 60975058 · Sep 25, 2007
Provisional Application 60983446 · Oct 29, 2007
Provisional Application 61024072 · Jan 28, 2008
Related Publication 20150004227A1 · Jan 1, 2015