IP Library Granted Patent US 10,383,877
Granted Patent B2
US 10,383,877 · App. 14/500,484 · Granted Aug 20, 2019

Use of substituted 2, 3-dihydroimidazo[1,2-c]quinazolines for the treatment of myeloma

Inventor: Ningshu Liu (Berlin, DE)
Assignee: BAYER INTELLECTUAL PROPERTY GMBH
A61K31/5377A61K31/519
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Quick Facts
Patent No.
US 10,383,877
App. No.
14/500,484
Granted
Aug 20, 2019
Kind
B2
Abstract

The present invention relates to the use of 2,3-dihydroimidazo[1,2-c]quinazoline compounds, and of pharmaceutical compositions containing such compounds, for the treatment or prophylaxis of multiple myeloma, as a sole agent or in combination with other one or more other active ingredients.

Claims (3)

1. A method for treatment of multiple myeloma comprising administering to a mammal in need thereof a pharmaceutically effective amount of 2-amino-N-[7-methoxy-8-(3-morpholin-4-ylpropoxy)-2,3-dihydroimidazo[1,2-c]quinazolin-5-yl]pyrimidine-5-carboxamide, or a physiologically acceptable salt, solvate, hydrate or stereoisomer thereof.

2. The method of claim 1 , wherein the method comprises administering 2-amino-N-[7-methoxy-8-(3-morpholin-4-ylpropoxy)-2,3-dihydroimidazo[1,2-c]quinazolin-5-yl]pyrimidine-5-carboxamide or a physiologically acceptable salt thereof.

3. The method of claim 1 , wherein the mammal in need thereof is a human.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 7, 2015
From: LIU, NINGSHU, DR.
To: BAYER SCHERING PHARMA AKTIENGESELLSCHAFT
Reel/Frame 035346/0772 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 7, 2015
From: BAYER PHARMA AKTIENGESELLSCHAFT
To: BAYER INTELLECTUAL PROPERTY GMBH
Reel/Frame 035347/0560 →
CHANGE OF NAME Recorded Apr 7, 2015
From: BAYER SCHERING PHARMA AKTIENGESELLSCHAFT
To: BAYER PHARMA AKTIENGESELLSCHAFT
Reel/Frame 035383/0947 →
Priority Claims (1)
EP 08164988 · Sep 24, 2008 · regional
Continuity (2)
Continuation 13120548
Related Publication 20150141420A1 · May 21, 2015