Network of participants in a shipment cold-chain

1. A process of receiving proposals relating to increasing the likelihood that a cargo will travel an entire shipment route without temperature excursions which exceed specified time periods, comprising:

establishing a website having participants, wherein the website is capable of receiving data from the shipment and displaying it for participants;

selecting a system of containers and solid phase refrigerants, which change from solid phase to liquid phase during shipment but not to gas phase and which are likely to maintain the cargo such that temperature excursions above a specified magnitude do not exceed specified time periods during the shipment period;

determining the maximum predicted period of shipment for the cargo and the predicted ambient temperature ranges during shipment;

shipping the products in the selected system and monitoring the temperatures encountered to a certain point during the shipment period using an on board monitor which monitors the temperature throughout the shipment period;

calculating the amount of the solid phase of the refrigerant remaining at said point during the shipment period based on the temperatures encountered by it and the time of exposure to different temperatures;

calculating a value, at said point during shipment, representing the likelihood that the remaining un-melted solid phase refrigerant is sufficient to preserve the biological products for the remaining shipment period, based on the expected ambient temperature range during said remaining shipment period; and

providing the value to participants and requesting proposals from participants where they take action to do one or more of: adding refrigerant to the shipment, moving the shipment to a faster transportation mode, moving the shipment to a temperature-controlled environment, or diverting the shipment to a different recipient.

2. The process of claim 1 wherein the requested action relates to reducing the risk that the remaining un-melted solid phase refrigerant is insufficient to maintain the cargo such that the temperatures encountered by it and the time of exposure to temperatures beyond upper and lower thresholds do not exceed a specified value.

3. The process of claim 1 wherein the on board monitor also records the temperature and exposure time throughout the shipment period.

4. The process of claim 3 wherein the recording by the on board monitor is in a file format which can be read by software readers.

5. The process of claim 4 wherein the file format is text.

6. The process of claim 4 further including downloading the file with the recorded temperatures and time of exposure to another device capable of reading the file format.

7. The process of claim 1 wherein the temperature-controlled environment is a refrigeration unit or a refrigerated cargo hold in a train, airplane or truck.

8. The process of claim 1 wherein the solid phase refrigerants are dry ice, ice, frozen gel packs, or phase change material or 1-dodecanol.

9. The process of claim 1 further including a GPS or other geo-location system to allow location of the shipment en route.

10. The process of claim 1 wherein the relative humidity, pressure and CO 2 is also monitored during shipment.

11. A process relating to increasing the likelihood that a cargo will travel an entire shipment route without temperature excursions which exceed specified time periods, comprising:

establishing a website wherein the website is capable of receiving data from the shipment and displaying it;

selecting a system of containers and solid phase refrigerants, which change from solid phase to liquid phase during shipment but not to gas phase and which are likely to maintain the cargo such that temperature excursions above a specified magnitude do not exceed specified time periods during the shipment period;

determining the maximum predicted period of shipment for the cargo and the predicted ambient temperature ranges during shipment;

shipping the products in the selected system;

recording the temperatures encountered to a certain point during the shipment period using an on board monitor which monitors the temperature throughout the shipment period and records it;

calculating the amount of the solid phase of the refrigerant remaining at said point during the shipment period based on the temperatures encountered by it and the time of exposure to different temperatures;

calculating a value, at said point during shipment, representing the likelihood that the remaining un-melted solid phase refrigerant is sufficient to preserve the biological products for the remaining shipment period, based on the expected ambient temperature range during said remaining shipment period; and

where if said likelihood is below a threshold, transmitting messages from the website to third parties requesting the third parties to do one or more of: adding refrigerant to the shipment, moving the shipment to a faster transportation mode, moving the shipment to a temperature-controlled environment, or diverting the shipment to a different recipient.

12. The process of claim 11 wherein the recording by the on board monitor is in a file format which can be read by software readers.

13. The process of claim 12 wherein the file format is text.

14. The process of claim 12 further including downloading the file with the recorded temperatures and time of exposure to another device capable of reading the file format.

15. The process of claim 11 wherein the temperature-controlled environment is a refrigeration unit or a refrigerated cargo hold in a train, airplane or truck.

16. The process of claim 11 wherein the solid phase refrigerants are dry ice, ice, frozen gel packs, or phase change material or 1-dodecanol.

17. The process of claim 11 further including a GPS or other geo-location system to allow location of the shipment en route.

18. The process of claim 11 wherein the relative humidity, pressure and CO 2 is also monitored during shipment.