IP Library Granted Patent US 10,386,435
Granted Patent B2
US 10,386,435 · App. 14/535,143 · Granted Aug 20, 2019

Methods and systems for fast auto-calibrated reconstruction with random projection in parallel MRI

Inventors: Lei Leslie Ying (East Amherst, NY); Jingyuan Lv (Buffalo, NY)
Assignee: The Research Foundation for The State University of New York
G01R33/5611A61B5/055
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Quick Facts
Patent No.
US 10,386,435
App. No.
14/535,143
Granted
Aug 20, 2019
Kind
B2
Abstract

Methods and systems for fast auto-calibrated reconstruction with random projection in parallel MRI are disclosed. In one embodiment, calibration and reconstruction are accelerated by reducing the number of k-space data channels before calibration. During calibration, a random projection is performed in order to reduce the dimensionality of the calibration equation. The reduced-dimensionality equation is used to obtain the reconstruction coefficients, which are then used to synthesize reconstructed k-space data. The received and reconstructed k-space data together construct a parallel MRI image. Systems for fast GRAPPA reconstruction are disclosed comprising a processor configured, for example, through software, to collect k-space data, reduce the number of data channels, perform the random projection, solve a reduced calibration equation, and synthesize the k-space data to construct a final parallel MRI image.

Claims (55)

1. A method for constructing a parallel magnetic resonance image comprising:

receiving, at a processor, a plurality of k-space signals, each signal corresponding to a channel of a receiver coil;

selecting, using the processor, a subset of the plurality of k-space signals, wherein the subset does not include all of the plurality of k-space signals;

receiving, at the processor, a plurality of auto-calibration signals;

selecting, using the processor, a subset of the plurality of auto-calibration signals;

determining, using the processor, a first calibration equation associated with the selected auto-calibration signals and the selected k-space signals;

reducing, using the processor, the first calibration equation to a reduced calibration equation having a lesser dimensionality than the first calibration equation;

determining, using the processor, a plurality of reconstruction coefficients based on the reduced calibration equation, each coefficient corresponding to a channel of the receiver coil;

synthesizing, using the processor, reconstructed k-space data based on the plurality of reconstruction coefficients and received k-space signals; and

constructing, using the processor, a parallel magnetic resonance image based on the reconstructed k-space data.

2. The method of claim 1 , wherein each k-space signal comprises a combination of sample data corresponding to the parallel magnetic resonance image and sensitivity information of a channel.

3. The method of claim 1 , wherein the step of selecting a subset of the plurality of k-space signals is performed using principal component analysis.

4. The method of claim 1 , wherein the first calibration equation is reduced by randomly selecting a subset of the first calibration equation or multiplying the first calibration equation with a random projection matrix.

5. The method of claim 4 , wherein the random projection matrix comprises elements from the following distribution:

R

(

i

,

j

)

=

3

{

1

p

=

1

/

6

0

p

=

2

/

3

-

1

p

=

1

/

6

6. The method of claim 1 , wherein the plurality of reconstruction coefficients are determined using a least-squares method.

7. The method of claim 1 , wherein the plurality of reconstruction coefficients are determined using a cost function minimization algorithm.

8. The method of claim 6 , wherein the cost function minimization algorithm calculates the plurality of reconstruction coefficients under a specified constraint.

9. The method of claim 7 , wherein the constraint is 1 1 -norm or 1 2 -norm.

10. The method of claim 1 , wherein the plurality of reconstruction coefficients are also based on a sensitivity of the receiver coil.

11. The method of claim 1 , wherein the step of selecting a subset of the plurality of k-space signals comprises:

defining, using the processor, a set of N vectors, where N equals the total number of channels associated with the plurality of k-space signals;

calculating, using the processor, a mean corresponding to each vector in the set of N vectors;

subtracting from each vector in the set of N vectors, using the processor, the calculated mean from the corresponding vector;

calculating, using the processor, a plurality of eigenvectors of a covariance matrix;

creating, using the processor, a compression matrix based on the plurality of eigenvectors; and

selecting, using the processor, a subset of the plurality of k-space signals by multiplying the plurality of k-space signals by the compression matrix.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 12, 2019
From: YING, LEI LESLIE; LV, JINGYUAN
To: THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK
Reel/Frame 048867/0087 →
CONFIRMATORY LICENSE Recorded Nov 3, 2015
From: STATE UNIVERSITY OF NEW YORK, BUFFALO
To: NATIONAL SCIENCE FOUNDATION
Reel/Frame 037040/0884 →
Continuity (2)
Provisional Application 61900574 · Nov 6, 2013
Related Publication 20150127291A1 · May 7, 2015