Patent Application
App. No. 14/537,429
METHOD FOR TREATING PROSTATITIS UTILIZING PORE-FORMING PROTEIN PROAEROLYSIN
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Abstract
The present disclosure includes methods and compositions for treating any condition involving prostatitis and similar diseases and/or conditions. These methods and compositions involve the use of targeted modified pore-forming proteins, including variant proaerolysin proteins.
Claims (4)
1 - 20 . (canceled)
21 . A method of treating prostatitis in a subject, comprising administering to said subject a therapeutically effective amount of PRX302,
wherein the PRX302 comprises:
an amino acid sequence having greater than 98% sequence identity to the amino acid sequence shown in SEQ ID NO:3 and which maintains the ability to selectively target and kill normal prostate cells, and an affinity tag.
Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Aug 22, 2016
From: NICKEL, CURTIS, DR.
To: PROTOX THERAPEUTICS, INC.
Reel/Frame 039499/0172 →
CHANGE OF NAME
Recorded Aug 22, 2016
From: PROTOX THERAPEUTICS, INC.
To: SOPHIRIS BIO INC.
Reel/Frame 039499/0790 →