Monodispersed particles fabricated by microfluidic device
According to various embodiments the present disclosure provides porous particles and methods and apparatus for forming porous microparticles. According to a specific embodiment, the present disclosure provides microparticles with multi-nodal porosity and methods for forming the same. According to a still further embodiment, the present disclosure provides microfluidic device-based methods for forming microparticles with multi-nodal nanoporosity. Furthermore, the present disclosure provides populations of monosdisperse mesoporous microparticles with multi-nodal nanoporosity and methods and apparatus for forming the same. According to a specific embodiment, the present disclosure provides populations of monodisperse mesoporous microparticles formed using a microfluidic device.
1. A porous spherical microparticle having a bimodal population of pores wherein:
at least 95% of the pores in the particle conform into two distinct populations, wherein each population is differentiatable by the average diameter of the pores in the population:
a first larger diameter pore population resulting from templating of microemulsion droplets; and
a second smaller diameter pore population resulting from templating of micelles.
2. The porous spherical microparticle of claim 1 wherein at least 99% of the pores in the particle conform into the two distinct populations.
3. The porous spherical microparticle of claim 1 wherein the particle is formed from silica.
4. The porous spherical microparticle of claim 1 wherein the particle has a smooth outer surface.
5. The porous spherical microparticle of claim 1 wherein the particle has a rough outer surface.
6. The porous spherical microparticle of claim 1 wherein the diameter of the pores in the first population is between 1 and 5% of the diameter of the particle and the diameter of the pores in the second population is between 0.3 and 0.9% of the diameter of the particle.
7. The porous spherical microparticle of claim 1 wherein the average diameter of the pores in the first population is between 3 and 7 μm and the average diameter of the pores in the second population is between 20 and 40 μm.