IP Library Granted Patent US 9,572,839
Granted Patent B2
US 9,572,839 · App. 14/585,114 · Granted Feb 21, 2017

Placental tissue grafts and methods of preparing and using the same

Inventor: John Daniel (Woodstock, GA)
Assignee: MiMedx Group, Inc.
A61K35/50A61F2/02A61J1/00A61L27/3604A61L27/3683A61L27/3687A61L27/3691A61L27/3695A61L27/40A61L27/50A61L27/54A61L27/58B65D25/205B65D81/18B65D85/70A61L2300/412A61L2300/60A61L2300/64A61L2430/40
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Quick Facts
Patent No.
US 9,572,839
App. No.
14/585,114
Granted
Feb 21, 2017
Kind
B2
Abstract

A method for preparing placenta membrane tissue grafts for medical use, includes obtaining a placenta from a subject, cleaning the placenta, separating the chorion tissue from the amniotic membrane, mounting a selected layer of either the chorion tissue or the amniotic membrane onto a drying fixture, dehydrating the selected layer on the drying fixture, and cutting the selected layer into a plurality of tissue grafts. Preferably, the drying fixture includes grooves or raised edges that define the outer contours of each desired tissue graft, after they are cut, and further includes raised or indented logos that emboss the middle area of the tissue grafts during dehydration and that enables an end user to distinguish the top from the bottom side of the graft. The grafts are comprised of single layers of amnion or chorion, multiple layers of amnion or chorion, or multiple layers of a combination of amnion and chorion.

Claims (2)

1. A laminated placental tissue graft consisting of a first chorion tissue layer and a second chorion tissue layer which is laminated to said first chorion tissue layer, wherein at least one of the chorion tissue layers is not decellularized, and wherein said tissue graft is dehydrated.

2. The laminated tissue graft of claim 1 , wherein the second chorion tissue layer is not decellularized.

Assignments (9)
RELEASE OF SECURITY INTEREST Recorded Feb 5, 2024
From: HAYFIN SERVICES LLP
To: MIMEDX GROUP, INC.; MIMEDX PROCESSING SERVICES, LLC
Reel/Frame 066493/0322 →
SECURITY INTEREST Recorded Jan 25, 2024
From: MIMEDX GROUP, INC.
To: CITIZENS BANK, N.A.
Reel/Frame 066371/0136 →
PATENT SECURITY AGREEMENT Recorded Jul 2, 2020
From: MIMEDX GROUP, INC.; MIMEDX PROCESSING SERVICES, LLC
To: HAYFIN SERVICES LLP, AS COLLATERAL AGENT
Reel/Frame 053121/0833 →
RELEASE OF SECURITY INTEREST Recorded Jul 2, 2020
From: BLUE TORCH FINANCE LLC, AS COLLATERAL AGENT
To: MIMEDX GROUP, INC.; MIMEDX PROCESSING SERVICES, LLC
Reel/Frame 054075/0687 →
SECURITY INTEREST Recorded Jun 11, 2019
From: MIMEDX GROUP, INC.
To: BLUE TORCH FINANCE LLC, AS COLLATERAL AGENT
Reel/Frame 049426/0863 →
TERMINATION AND RELEASE OF SECURITY INTEREST IN PATENTS Recorded Jan 24, 2019
From: BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT
To: MIMEDX GROUP, INC.
Reel/Frame 048121/0835 →
NOTICE OF GRANT OF SECURITY INTEREST IN PATENTS Recorded Oct 15, 2015
From: MIMEDX GROUP, INC.
To: BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT
Reel/Frame 036872/0498 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 9, 2015
From: SURGICAL BIOLOGICS, LLC
To: MIMEDX GROUP, INC.
Reel/Frame 036768/0858 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 9, 2015
From: DANIEL, JOHN
To: SURGICAL BIOLOGICS, LLC.
Reel/Frame 036768/0861 →
Continuity (7)
Continuation 14335698 · Jul 18, 2014
Continuation 14222510 · Mar 21, 2014
Continuation 13954974 · Jul 30, 2013
Continuation 13569095 · Aug 7, 2012
Continuation 11840728 · Aug 17, 2007
Provisional Application 60838467 · Aug 17, 2006
Related Publication 20150110850A1 · Apr 23, 2015