DEVICES AND METHODS FOR DELIVERING A BENEFICIAL AGENT TO A USER
Drug delivery reservoir cassette for a pump is provided. The cassette includes a cassette housing having a front surface, a back surface and lateral sidewalls, the cassette housing defining a transverse axis extending between the lateral sidewalls and a longitudinal axis perpendicular to the transverse axis. The cassette housing includes a cassette body region defining a fluid reservoir chamber therein, and a cassette base region having a boundary configured to be received by the pump, the boundary including a pair of opposing rails disposed on opposite sides of the longitudinal axis. The cassette base region can also include an engagement surface, alignment key, and/or support rib to align the cassette in a receiving region of the pump. A device for delivering a beneficial agent including a pump and cassette is also provided.
1 . A drug delivery reservoir cassette for a pump, the pump having a lock member movable between an open position and a closed position, the cassette comprising:
a cassette housing having a front surface, a back surface and lateral sidewalls, the cassette housing defining a transverse axis extending between the lateral sidewalls and a longitudinal axis perpendicular to the transverse axis, the cassette housing including:
a cassette body region defining a fluid reservoir chamber therein, and
a cassette base region having a boundary configured to be received by the pump, the boundary including a pair of opposing rails disposed on opposite sides of the longitudinal axis.
2 . The cassette of claim 1 , wherein the pair of opposing rails are substantially symmetrical about the longitudinal axis.
3 . The cassette of claim 1 , wherein each of the opposing rails is recessed relative an adjacent portion of the boundary.
4 . The cassette of claim 1 , wherein the pair of opposing rails are aligned along a transverse axis relative the longitudinal axis.
5 . The cassette of claim 4 , wherein each of opposing rails defines an abutment surface generally parallel with the transverse axis.
6 . The cassette of claim 1 , wherein the cassette base region includes an engagement surface configured to be engaged by the lock member when in the closed position.
7 . The cassette of claim 6 , wherein the pair of rails are spaced from the engagement surface in a direction along the longitudinal axis.
8 . The cassette of claim 6 , wherein the boundary includes an alignment key aligned parallel with the longitudinal axis and defining a receiving recess to receive an alignment pin from the pump.
9 . The cassette of claim 8 , wherein the alignment key is spaced from the pair of rails and from the engagement surface in a direction along the longitudinal axis.
10 . The cassette of claim 8 , wherein the cassette further comprises a delivery tube assembly extending from the fluid reservoir chamber, and the cassette base region includes a support rib projecting from the boundary in engagement with the delivery tube.
11 . The cassette of claim 10 , wherein the cassette base region includes a flat surface proximate an end of the cassette housing.
12 . The cassette of claim 11 , wherein the flat surface comprises two flat surface portions.
13 . The cassette of claim 11 , wherein the cassette base region includes a contoured surface configured to mate a corresponding surface of the pump.
14 . The cassette of claim 13 , wherein the contoured surface has a concave shape directed toward the boundary in plan view.
15 . The cassette of claim 13 , wherein the contoured surface is substantially symmetrical about the longitudinal axis.
16 . The cassette of claim 1 , further comprising a beneficial agent contained in the fluid reservoir.
17 . The cassette of claim 16 , wherein the beneficial agent comprises one or more of levodopa and carbidopa.
18 . A drug delivery reservoir cassette for a pump, the pump having a lock member movable between an open position and a closed position, the cassette comprising:
a cassette housing having a front surface, a back surface and lateral sidewalls, the cassette housing defining a transverse axis extending between the lateral sidewalls and a longitudinal axis perpendicular to the transverse axis, the cassette housing including:
a cassette body region defining a fluid reservoir chamber therein, and
a cassette base region having a boundary configured to be received by the pump, the cassette base region including an engagement surface configured to be engaged by the lock member when in the closed position.
19 . The cassette of claim 18 , wherein the engagement surface is substantially coplanar with the back surface of the cassette housing.
20 . The cassette of claim 18 , wherein the engagement surface comprises a recessed area recessed relative the back surface of the cassette base region.
21 . The cassette of claim 20 , wherein the recessed area is shaped to receive the lock member when in the closed position.
22 . The cassette of claim 20 , wherein the recessed area tapers to a smaller cross dimension toward an end of the cassette housing.
23 . The cassette of claim 18 , wherein the engagement surface comprises a pair of engagement surface portions on opposite sides of the longitudinal axis.
24 . The cassette of claim 23 , wherein the pair of engagement surface portions are substantially symmetrical about the longitudinal axis.
25 . The cassette of claim 18 , wherein the engagement surface comprises an elongated strip.
26 . The cassette of claim 18 , wherein the engagement surface comprises a unitary bridge across the longitudinal axis.
27 . The cassette of claim 18 , wherein the boundary includes an alignment key aligned parallel with the longitudinal axis and defining a receiving recess to receive an alignment pin from the pump.
28 . The cassette of claim 27 , wherein the cassette further comprises a delivery tube assembly extending from the fluid reservoir chamber, and the cassette base region includes a support rib projecting from the boundary in engagement with the delivery tube.
29 . The cassette of claim 28 , wherein the support rib is disposed proximate the engagement surface.
30 . The cassette of claim 28 , wherein the cassette base region includes a flat surface proximate an end of the cassette housing.
31 . The cassette of claim 30 , wherein the flat surface comprises two flat surface portions.
32 . The cassette of claim 31 , wherein the engagement surface comprises a bridge portion joining the two flat surface portions.
33 . The cassette of claim 28 , wherein the cassette base region includes a contoured surface configured to mate a corresponding surface of the pump.
34 . The cassette of claim 18 , further comprising a beneficial agent contained in the fluid reservoir.
35 . The cassette of claim 34 , wherein the beneficial agent comprises one or more of levodopa and carbidopa.
36 . A drug delivery reservoir cassette for a pump, the pump having a lock member movable between an open position and a closed position, the cassette comprising:
a cassette housing having a front surface, a back surface and lateral sidewalls, the cassette housing defining a transverse axis extending between the lateral sidewalls and a longitudinal axis perpendicular to the transverse axis, the cassette housing including:
a cassette body region defining a fluid reservoir chamber therein, and
a cassette base region having a boundary configured to be received by the pump, the boundary including an alignment key aligned parallel with the longitudinal axis and defining a receiving recess to receive an alignment pin from the pump.
37 . The cassette of claim 36 , wherein the alignment key is centered between the lateral side walls.
38 . The cassette of claim 36 , wherein the alignment key projects into the boundary.
39 . The cassette of claim 36 , wherein the alignment key projects from the cassette body region into the cassette base region.
40 . The cassette of claim 36 , wherein the alignment key is channel-shaped.
41 . The cassette of claim 36 , wherein the receiving recess is tapered along the longitudinal axis.
42 . The cassette of claim 36 , wherein the cassette further comprises a delivery tube assembly extending from the fluid reservoir chamber, and the cassette base region includes a support rib projecting from the boundary in engagement with the delivery tube.
43 . The cassette of claim 42 , wherein the cassette base region includes a flat surface proximate an end of the cassette housing.
44 . The cassette of claim 43 , wherein the cassette base region includes a contoured surface configured to mate a corresponding surface of the pump.
45 . The cassette of claim 36 , further comprising a beneficial agent contained in the fluid reservoir.
46 . The cassette of claim 45 , wherein the beneficial agent comprises one or more of levodopa and carbidopa.
47 . A drug delivery reservoir cassette for a pump, the pump having a lock member movable between an open position and a closed position, the cassette comprising:
a cassette housing having a front surface, a back surface and lateral sidewalls, the cassette housing defining a transverse axis extending between the lateral sidewalls and a longitudinal axis perpendicular to the transverse axis, the cassette housing including:
a cassette body region defining a fluid reservoir chamber therein, and
a cassette base region having a boundary configured to be received by the pump, wherein the cassette further comprises a delivery tube assembly extending from the fluid reservoir chamber, and the cassette base region includes a support rib projecting from the boundary in engagement with the delivery tube.
48 . The cassette of claim 47 , wherein the support rib comprises a pair of support rib portions.
49 . The cassette of claim 47 , wherein the delivery tube assembly includes a pair of end fittings to receive a peristaltic tube, and further wherein the support rib is substantially aligned between the pair of end fittings.
50 . The cassette of claim 47 , wherein the cassette base region includes a flat surface proximate an end of the cassette housing.
51 . The cassette of claim 50 , wherein the cassette base region includes a contoured surface configured to mate a corresponding surface of the pump.
52 . The cassette of claim 47 , further comprising a beneficial agent contained in the fluid reservoir.
53 . The cassette of claim 52 , wherein the beneficial agent comprises one or more of levodopa and carbidopa.
54 . A device for delivering a beneficial agent, comprising:
a pump including a pump housing containing a pump assembly having a fluid drive component, the pump housing having a receiving region disposed proximate the fluid drive component; and
a cassette including a cassette housing having a front surface, a back surface and lateral sidewalls, the cassette housing defining a transverse axis extending between the lateral sidewalls and a longitudinal axis perpendicular to the transverse axis, the cassette housing including:
a cassette body region defining a fluid reservoir chamber therein, and
a cassette base region having a boundary configured to be received by the receiving region, the boundary including a pair of opposing rails disposed on opposite sides of the longitudinal axis.
55 . The device of claim 54 , wherein the pair of opposing rails are substantially symmetrical about the longitudinal axis.
56 . The device of claim 54 , wherein each of the opposing rails is recessed relative an adjacent portion of the boundary.
57 . The device of claim 54 , wherein the pair of opposing rails are aligned along a transverse axis relative the longitudinal axis.
58 . The device of claim 57 , wherein each of opposing rails defines an abutment surface generally parallel with the transverse axis.
59 . The device of claim 54 , wherein the cassette base region includes an engagement surface configured to be engaged by the lock member when in the closed position.
60 . The device of claim 59 , wherein the pair of rails are spaced from the engagement surface in a direction along the longitudinal axis.
61 . The device of claim 59 , wherein the boundary includes an alignment key aligned parallel with the longitudinal axis and defining a receiving recess to receive an alignment pin from the pump.
62 . The device of claim 61 , wherein the alignment key is spaced from the pair of rails and from the engagement surface in a direction along the longitudinal axis.
63 . The device of claim 61 , wherein the device further comprises a delivery tube assembly extending from the fluid reservoir chamber, and the cassette base region includes a support rib projecting from the boundary in engagement with the delivery tube.
64 . The device of claim 61 , wherein the cassette base region includes a flat surface proximate an end of the cassette housing.
65 . The device of claim 64 , wherein the flat surface comprises two flat surface portions.
66 . The device of claim 64 , wherein the cassette base region includes a contoured surface configured to mate a corresponding surface of the pump.
67 . The device of claim 66 , wherein the contoured surface has a concave shape directed toward the boundary in plan view.
68 . The device of claim 66 , wherein the contoured surface is substantially symmetrical about the longitudinal axis.
69 . The device of claim 54 , further comprising a beneficial agent contained in the fluid reservoir.
70 . The device of claim 69 , wherein the beneficial agent comprises one or more of levodopa and carbidopa.