IP Library Granted Patent US 9,452,190
Granted Patent B2
US 9,452,190 · App. 14/597,674 · Granted Sep 27, 2016

Neuroprotective natural extract from passion fruit

Inventors: Alon Samach (Rehovot, IL); Oren Tirosh (Nes Ziona, IL); Edna Pesis (Nes Ziona, IL); Avital Artan (Rehovot, IL); Livnat Goldenberg (Rehovot, IL); Aron Troen (Mazkeret Batya, IL)
Assignees: THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANISATION (ARO) (VOLCANI CENTER); YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD.
A61K36/185A23L1/2225A23L1/3002A23V2002/00
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Quick Facts
Patent No.
US 9,452,190
App. No.
14/597,674
Granted
Sep 27, 2016
Kind
B2
Abstract

Methods for the treatment and prevention of neural cell and neuro-pathological disorders are provided, comprising contacting the neural cells, or administering to a subject in need thereof, botanical raw material (BRM) or an extract obtainable from passion fruits. Compositions, as well as a nutraceutical composition comprising the same are also provided.

Claims (8)

1. A method for protecting neural cells in a subject having age-related neurodegeneration, said method comprising the step of administering to said subject an effective amount of botanical raw material (BRM) or an extract obtained from passion fruits, wherein said BRM or an extract obtained from passion fruits is any one of a juice or seeds obtained from passion fruits, or any concentrate or preparation obtained from said juice or seeds.

2. The method according to claim 1 , wherein said BRM or an extract obtained from passion fruits is any one of a juice or seeds obtained from at least one variety or cultivar of passion fruits or a mixture of two or more cultivars of passion fruits, or any concentrate or preparation obtained from said juice or seeds.

3. The method according to claim 1 , wherein said BRM or an extract obtained from passion fruits is administered as part of a nutraceutical composition, pharmaceutical composition, functional food, functional nutrition product, medical food, medical nutrition product or dietary supplement.

4. A method for protecting from, inhibiting or reducing cognitive decline in a subject having age-related neurodegeneration, said method comprising the step of administering to said subject an effective amount of botanical raw material (BRM) or an extract obtained from passion fruits, wherein said BRM or an extract obtained from passion fruits is any one of a juice or seeds obtained from passion fruits, or any concentrate or preparation obtained from said juice or seeds.

5. The method according to claim 4 , wherein said BRM or an extract obtained from passion fruits is any one of a juice or seeds obtained from at least one variety or cultivar of passion fruits or a mixture of two or more cultivars of passion fruits, or any concentrate or preparation obtained from said juice or seeds.

6. The method according to claim 4 , wherein said BRM or an extract obtained from passion fruits is administered as part of a nutraceutical composition, pharmaceutical composition, functional food, functional nutrition product, medical food, medical nutrition product or dietary supplement.

7. A method for the treatment, amelioration or inhibition of age-related neurodegeneration in a subject having age-related neurodegeneration, said method comprising the step of administering to said subject an effective amount of BRM or an extract obtained from passion fruits, wherein said BRM or an extract obtained from passion fruits is any one of a juice or seeds obtained from passion fruits, or any concentrate or preparation obtained from said juice or seeds, wherein said subject has age-related neurodegeneration.

8. The method according to claim 7 , wherein said BRM or an extract obtained from passion fruits is administered as part of a nutraceutical composition, pharmaceutical composition, functional food, functional nutrition product, medical food, medical nutrition product or dietary supplement.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 27, 2023
From: TALENTSPHERE, LLC
To: RELAPHI, LLC
Reel/Frame 064074/0298 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 30, 2015
From: SAMACH, ALON; TIROSH, OREN; ARTAN, AVITAL; GOLDENBERG, LIVNAT; TROEN, ARON
To: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD.
Reel/Frame 035285/0366 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 30, 2015
From: PESIS, EDNA
To: THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANISATION (ARO) (VOLCANI CENTER)
Reel/Frame 035285/0437 →
Continuity (3)
Continuation 13807024
Provisional Application 61359073 · Jun 28, 2010
Related Publication 20150182569A1 · Jul 2, 2015