IP Library Granted Patent US 9,980,975
Granted Patent B2
US 9,980,975 · App. 14/603,224 · Granted May 29, 2018

Dosage forms containing fluticasone propionate for the treatment of inflammatory conditions of the esophagus

Inventors: Giancarlo Santus (Milan, IT); Leticia Khater Covesi (São Paulo, BR); Luca Donadoni (Alzano Lombardo, IT); Christina Ecclissato (São Paulo, BR); Roberto Amazonas (São Paulo, BR)
Assignee: EMS S.A.
A61K31/56A61K9/0095A61K47/14A61K47/26A61K47/32A61K47/36A61K47/38
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Quick Facts
Patent No.
US 9,980,975
App. No.
14/603,224
Granted
May 29, 2018
Kind
B2
Abstract

The present invention describes novel and improved dosage forms containing fluticasone propionate for the treatment of conditions associated with inflammation of the esophagus.

Claims (7)

1. A liquid pharmaceutical composition comprising fluticasone propionate in combination with 2.0 wt % of sodium alginate as viscosity enhancer and other non-active ingredients, said non-active ingredients comprising:

(i) 0.075 wt % of sucralose as edulcorant;

(ii) 0.1 wt % of carbomer as suspending agent;

(iii) 0.002 wt % of polysorbate 80 as wetting agent surfactant; and

(iv) about 0.2 wt % of a mixture of methylparaben and propylparaben as preservative; and

(v) sodium hydroxide,

wherein the liquid pharmaceutical composition is formulated for oral administration and has a pH between 6.5 and 7.5.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 11, 2015
From: SANTUS, GIANCARLO; COVESI, LETICIA KHATER; DONADONI, LUCA; ECCLISSATO, CHRISTINA; AMAZONAS, ROBERTO
To: EMS S.A.
Reel/Frame 034940/0969 →
Continuity (1)
Related Publication 20160213681A1 · Jul 28, 2016