IP Library › Granted Patent US 10,159,670
Granted Patent B2
US 10,159,670 · App. 14/612,034 · Granted Dec 25, 2018

Methods of diagnosing and treating motor neuron diseases and other cellular stress-related diseases

Inventors: Eran Hornstein (Rehovot, IL); Anna Maria Emde (Rehovot, IL)
Assignee: Yeda Research and Development Co. Ltd.
A61K31/496A61K31/538A61K45/06
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Quick Facts
Patent No.
US 10,159,670
App. No.
14/612,034
Granted
Dec 25, 2018
Kind
B2
Abstract

A method of treating a cellular stress-related disease in a subject in need thereof is provided. The method comprising administering to the subject a therapeutically effective amount of an agent capable of enhancing processing of a pre-miRNA, thereby treating the cellular stress-related disease in the subject. Methods for treating motor neuron disease (MND) are also provided as well as pharmaceutical compositions.

Claims (2)

1. A method of treating Amyotrophic Lateral Sclerosis (ALS) in a subject in need thereof, the method comprising administering to the subject a therapeutically effective amount of enoxacin, thereby treating the ALS in the subject.

2. The method of claim 1 , further comprising administering to the subject an anti-ALS agent.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 22, 2015
From: HORNSTEIN, ERAN; EMDE, ANNA MARIA
To: YEDA RESEARCH AND DEVELOPMENT CO. LTD.
Reel/Frame 035000/0913 →
Continuity (3)
Continuation In Part PCTIL2013050655 · Jul 31, 2013
Provisional Application 61677494 · Jul 31, 2012
Related Publication 20150164891A1 · Jun 18, 2015