IP Library › Granted Patent US 10,065,958
Granted Patent B2
US 10,065,958 · App. 14/613,719 · Granted Sep 4, 2018

Methods and compounds for treating Paramyxoviridae virus infections

Inventors: Richard L. Mackman (Milbrae, CA); Jay P. Parrish (Redwood City, CA); Adrian S. Ray (Redwood City, CA); Dorothy Agnes Theodore (Castro Valley, CA)
Assignee: GILEAD SCIENCES, INC.
C07D487/04A61K9/0078A61K31/706A61K45/06C07F9/6561C07H7/06C07H19/04
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Quick Facts
Patent No.
US 10,065,958
App. No.
14/613,719
Granted
Sep 4, 2018
Kind
B2
Abstract

Provided are methods for treating Paramyxoviridae virus infections by administering ribosides, riboside phosphates and prodrugs thereof, of Formula I: wherein the 1′ position of the nucleoside sugar is substituted. The compounds, compositions, and methods provided are particularly useful for the treatment of Human parainfluenza and Human respiratory syncytial virus infections.

Claims (3)

1. A compound that is

or a pharmaceutically acceptable salt or ester thereof.

2. A compound

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 23, 2015
From: MACKMAN, RICHARD L.; PARRISH, JAY P.; RAY, ADRIAN S.; THEODORE, DOROTHY AGNES
To: GILEAD SCIENCES, INC.
Reel/Frame 035481/0861 →
Continuity (3)
Continuation 13189373 · Jul 22, 2011
Provisional Application 61366609 · Jul 22, 2010
Related Publication 20150152116A1 · Jun 4, 2015
Cited By (7)
US 12,227,520 US 12,297,226 US 12,357,577 US 12,404,289 US 12,448,383 US 12,509,466 US 12,655,172