GAS CONDITIONING
A method for reducing or preventing mesothelial cell damage by mixing a carrier gas and between 1 volume percent and 29 volume percent of nitrous oxide gas (N 2 O) to form a medicament and applying the medicament during surgery. The method can be used for prevention of adhesion formation, pain reduction, reducing or preventing acute inflammation, reducing or preventing CO 2 resorbtion or reducing tumor cell implantation upon surgery.
1 - 31 . (canceled)
32 . A method for reducing or preventing mesothelial cell damage during surgery comprising the steps of:
mixing a carrier gas and nitrous oxide gas to form a medicament, wherein the nitrous oxide gas is between 1 volume percent and 29 volume percent, and
applying the medicament during surgery to reduce or prevent mesothelial cell damage.
33 . The method of claim 32 , wherein the nitrous oxide gas is between 5 and 20 volume percent.
34 . The method of claim 33 , wherein the nitrous oxide gas is between 5 and 10 volume percent.
35 . The method of claim 32 , wherein the carrier gas is carbon dioxide gas.
36 . The method of claim 33 , wherein the solubility of the carrier gas is larger than 0.5 g/l in water.
37 . The method of claim 32 , wherein applying the medicament comprises flowing the medicament in or over a cavity during surgery in a cavity.
38 . The method of claim 32 , wherein applying the medicament comprises flowing the medicament during pneumoperitoneum.
39 . The method of claim 32 , wherein applying the medicament comprises flowing the medicament during open surgery.
40 . The method according to claim 32 , wherein applying the medicament during surgery furthermore comprises applying the medicament for reducing or preventing pain.
41 . The method according to claim 32 , wherein applying the medicament during surgery furthermore comprises applying the medicament for reducing or preventing acute inflammation.
42 . The method according to claim 32 , wherein applying the medicament during surgery furthermore comprises applying the medicament for reducing or preventing CO2 resorbtion.
43 . The method according to claim 32 , wherein applying the medicament during surgery furthermore comprises applying the medicament for reducing tumor implantation reduction.
44 . The method according to claim 32 , wherein applying the medicament during surgery furthermore comprises applying the medicament for reducing or preventing adhesion formation.