IP Library › Granted Patent US 9,687,534
Granted Patent B2
US 9,687,534 · App. 14/639,425 · Granted Jun 27, 2017

Pharmaceutical preparation for the treatment of the symptoms of addiction and method of diagnosing same

Inventor: Joan M. Fallon (Bronxville, NY)
Assignee: Curemark, LLC
A61K38/54A61K38/465A61K38/47A61K38/4826A61K38/4873
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Quick Facts
Patent No.
US 9,687,534
App. No.
14/639,425
Granted
Jun 27, 2017
Kind
B2
Abstract

A therapeutic agent for the treatment of the symptoms of addiction and the method for preparing the therapeutic agent is disclosed. The therapeutic agent is a stable pharmaceutical preparation containing, but not limited to, digestive/pancreatic enzymes. The therapeutic agent may be manufactured by a variety of encapsulation technologies. Delivery of the therapeutic agent may be made orally, through injection, by adherence of a medicated patch or other method. Further, a method of using of a biomarker, the presence of chymotrypsin in the gastrointestinal tract to determine the presence of symptoms of addiction, and the likelihood of relapsing into addiction is disclosed.

Claims (18)

1. A method for treating an individual exhibiting one or more symptoms of an addiction, wherein the addiction is a cocaine addiction, the method comprising, administering to the individual a therapeutically effective amount of a pharmaceutical preparation comprising digestive enzymes, whereby the one or more symptoms of the individual's cocaine addiction are treated.

2. The method of claim 1 , wherein the digestive enzymes comprise an amylase, a lipase, and a protease.

3. The method of claim 1 , wherein the digestive enzymes consist of an amylase, a lipase, and a protease.

4. The method of claim 1 , wherein the digestive enzymes are selected from the group consisting of animal enzymes, plant enzymes, synthetic enzymes, and a combination thereof.

5. The method of claim 1 , wherein the pharmaceutical preparation is manufactured using a technology selected from the group consisting of enteric coating, lipid encapsulation, direct compression, dry granulation, wet granulation, and a combination thereof.

6. The method of claim 1 , wherein the pharmaceutical preparation is administered orally via a dosage formulation selected from the group consisting of a pill, a tablet, a capsule, a microcapsule, a mini-capsule, a time released capsule, a mini-tab, a sprinkle, and a combination thereof.

7. The method of claim 2 , wherein the amylase is present in the pharmaceutical preparation in amount of from 10,000 to 60,000 U.S.P. units/dose.

8. The method of claim 2 , wherein the protease is present in the pharmaceutical preparation in amount of from 10,000 to 70,000 U.S.P. units/dose.

9. The method of claim 2 , wherein the lipase is present in the pharmaceutical preparation in amount of from 4,000 to 30,000 U.S.P. units/dose.

10. A method of treating an individual with an addiction, wherein the addiction is a cocaine addiction, the method comprising administering to the individual a therapeutically effective amount of a pharmaceutical preparation comprising digestive enzymes, whereby the individual's cocaine addiction is treated.

11. The method of claim 10 , wherein the digestive enzymes comprise an amylase, a lipase, and a protease.

12. The method of claim 10 , wherein the digestive enzymes consist of an amylase, a lipase, and a protease.

13. The method of claim 10 , wherein the digestive enzymes are selected from the group consisting of animal enzymes, plant enzymes, synthetic enzymes, and a combination thereof.

14. The method of claim 10 , wherein the pharmaceutical preparation is manufactured using a technology selected from the group consisting of enteric coating, lipid encapsulation, direct compression, dry granulation, wet granulation, and a combination thereof.

15. The method of claim 10 , wherein the pharmaceutical preparation is administered orally via a dosage formulation selected from the group consisting of a pill, a tablet, a capsule, a microcapsule, a mini-capsule, a time released capsule, a mini-tab, a sprinkle, and a combination thereof.

16. The method of claim 11 , wherein the amylase is present in the pharmaceutical preparation in amount of from 10,000 to 60,000 U.S.P. units/dose.

17. The method of claim 11 , wherein the protease is present in the pharmaceutical preparation in amount of from 10,000 to 70,000 U.S.P. units/dose.

18. The method of claim 11 , wherein the lipase is present in the pharmaceutical preparation in amount of from 4,000 to 30,000 U.S.P. units/dose.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 5, 2015
From: FALLON, JOAN M.
To: CUREMARK, LLC
Reel/Frame 035094/0887 →
Continuity (6)
Continuation 13926822 · Jun 25, 2013
Continuation 13562999 · Jul 31, 2012
Continuation 13271783 · Oct 12, 2011
Continuation 12426794 · Apr 20, 2009
Provisional Application 61046026 · Apr 18, 2008
Related Publication 20150174219A1 · Jun 25, 2015