IP Library Granted Patent US 10,724,986
Granted Patent B2
US 10,724,986 · App. 14/648,497 · Granted Jul 28, 2020

Dielectric electrolyte measurement device

Inventors: Afshin Izadian (Indianapolis, IN); Robert L. Bacallao (Indianapolis, IN)
Assignee: Indiana University Research & Technology Corporation
G01N27/447B01D61/243B01D61/28G01N21/55G01N21/64
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Quick Facts
Patent No.
US 10,724,986
App. No.
14/648,497
Granted
Jul 28, 2020
Kind
B2
Abstract

A system, device and apparatus for measuring electrolytes, where an electrical charge is applied to a measurement portion to draw ions from a liquid to a gel-solution via at least one electric field. The gel-solution containing the extracted ions is excited with light of a predetermined wavelength from an emitter. A receiver detects the illumination of the ions as a result of the excited gel-solution, and a processor converts the detected intensities of the illumination to a biologically useful value representing ionic concentration.

Claims (31)

1. A system for monitoring electrolytes in a liquid, comprising:

a gel-solution;

a circuit configured to apply an electric field to separate ions from the liquid into the gel-solution;

a light emitter configured to excite the gel-solution, containing the ions, with light of a predetermined wavelength;

a receiver configured to optically detect the illumination of the ions in the gel-solution resulting from the excitation;

a processing device configured to determine intensities of the detected illumination, and to convert the intensities to a value representing one or more concentration values for the ions;

a dialysis membrane disposed between the liquid and the gel-solution such that the dialysis membrane permits the ions to penetrate the dialysis membrane and into the gel-solution based on the circuit applying the electric field; and

a glass membrane disposed on a surface of a conductive layer opposite a surface of the conductive layer in contact with a dielectric material, wherein

the circuit comprises:

an electrode;

the conductive layer; and

the dielectric material, wherein the dielectric material is disposed between the conductive layer and the gel-solution to provide conductive separation between the conductive layer and the gel-solution.

2. The system of claim 1 , wherein the circuit is configured to apply a DC electric field that is used to separate the ions from the liquid into the gel-solution in the direction of the conductive layer.

3. The system of claim 1 , wherein the light emitter comprises a photodiode and the receiver comprises a charge-coupled device (CCD) camera.

4. The system of claim 1 , wherein the processing device comprises a signal conditioning unit.

5. The system of claim 1 , wherein the gel-solution comprises one of (i) a fluorescing solution configured to assist in light radiation, and (ii) a chemical buffering agent.

6. The system of claim 1 , wherein the predetermined wavelength is between 300-500 nm.

7. The system of claim 1 , wherein the processing device comprises a look-up table for comparing the converted value for representing one or more concentration values for the ions.

8. A method for operating the system of claim 1 to monitor electrolytes in a liquid, comprising the steps of:

applying the electric field to separate ions from the liquid into the gel-solution;

exciting the gel-solution, containing the separated ions, with the light of the predetermined wavelength;

optically detecting the illumination of the ions in the gel-solution resulting from the excitation; and

converting the intensities of the detected illumination to the value representing the one or more concentration values for the ions, wherein a transparent second dielectric material is separated from the dielectric material by the conductive layer.

9. The method of claim 8 , wherein the gel-solution comprises a fluorescing solution configured to assist in light radiation.

10. The method of claim 9 , wherein the fluorescing solution comprises agarose.

11. The method of claim 8 , wherein the gel-solution comprises a chemical buffering agent.

12. The method of claim 11 , wherein the chemical buffering agent comprises sodium HEPES and an emulsifier.

13. The method of claim 8 , wherein the step of applying the electric field comprises generating a DC electric field between the electrode and the conductive layer, wherein the ions are separated from the liquid into the gel-solution in the direction of the conductive layer.

14. The method of claim 8 , wherein the predetermined wavelength is 300-500 nm.

15. The method of claim 8 , wherein the step of optically detecting the illumination comprises detecting illumination via a light measurement sensor.

16. The method of claim 8 , wherein converting the intensities of the detected illumination to the value representing the one or more concentration values for the ions comprises converting the detected illumination to one or more voltage values representing ion concentration.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 21, 2018
From: INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION
To: U.S. DEPARTMENT OF VETERAN AFFAIRS AS REPRESENTED BY THE TECHNOLOGY TRANSFER PROGRAM; INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION
Reel/Frame 046939/0288 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 7, 2015
From: IZADIAN, AFSHIN; BACALLAO, ROBERT
To: INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION
Reel/Frame 036015/0212 →
Continuity (2)
Provisional Application 61731039 · Nov 29, 2012
Related Publication 20150308978A1 · Oct 29, 2015