Neuregulin peptides and their use
View Patent ↗Neuregulin peptides useful, for example, in methods and compositions comprising preventing, treating or delaying various diseases or disorders are described.
1. A method for treating heart failure in a subject in need thereof comprising administering intravenously or subcutaneously to the subject and effective amount of neuregulin peptide consisting of the amino acid sequence of SEQ ID NO:3, SEQ ID NO:5, SEQ ID NO:7 or SEQ ID NO:9.
2. The method of claim 1 , wherein the neuregulin peptide consists of the amino acid sequence of SEQ ID NO:3.
3. The method of claim 2 , wherein the neuregulin peptide is administered intravenously.
4. The method of claim 2 , wherein the neuregulin peptide is administered subcutaneously.
5. The method of claim 1 , wherein the neuregulin peptide consists of the amino acid sequence of SEQ ID NO:5 and is administered intravenously.
6. The method of claim 1 , wherein the neuregulin peptide consists of the amino acid sequence of SEQ ID NO:5 and is administered subcutaneously.
7. The method of claim 1 , wherein the neuregulin peptide consists of the amino acid sequence of SEQ ID NO:7.
8. The method of claim 7 , wherein the neuregulin peptide is administered intravenously.
9. The method of claim 7 , wherein the neuregulin peptide is administered subcutaneously.
10. The method of claim 1 , wherein the neuregulin peptide consists of the amino acid sequence of SEQ ID NO:9.
11. The method of claim 10 , wherein the neuregulin peptide is administered intravenously.
12. The method of claim 10 , wherein the neuregulin peptide is administered subcutaneously.
13. The method of any one of claim 1 , 2 , 3 , 4 , 5 - 7 , 8 - 10 , 11 or 12 , wherein the subject is human.