Composition and method for medical imaging or body cavities
The present invention relates to an image enhancing composition for the enhancement of contrast in a body cavity, wherein the viscosity of the composition is between 2000 and 4000 mPa·sec. It also relates to a method for enhancing contrast of an image of a body cavity, which method comprises introducing one single small amounts of an image enhancing composition into the body cavity. In another aspect, the present invention provides a high contrast image of a body cavity obtained by the method of the invention, in particular a 3-dimensional high contrast image.
1. An echo-lucent image enhancing composition for the enhancement of contrast in a body cavity, wherein the composition comprises a cellulose derivative has a pH between 5.5 to 7.5 and a viscosity between 2000 to 4000 mPa·sec. when measured at room temperature wherein the composition is free of particulate matter that interfere with clear image formation.
2. The echo-lucent image enhancing composition according to claim 1 , wherein the viscosity of the composition is between 2700 and 3000 mPa·sec, when measured at room temperature.
3. The echo-lucent image enhancing composition according to claim 1 , wherein the composition is free of pyrrolidones, alcohols, disinfectants and anaesthetics.
4. The echo-lucent image enhancing composition according to claim 1 , wherein the cellulose derivative is hydroxyethylcellulose or methylcellulose.
5. The echo-lucent image enhancing composition according to claim 1 , wherein the composition provides enhancement of contrast in a uterine cavity.
6. The echo-lucent image enhancing composition according to claim 1 , wherein the composition provides for three dimensional imaging.
7. A method for enhancing contrast of an image of a body cavity, comprising the step of introducing an echo-lucent image enhancing composition according to claim 1 into the body cavity.
8. The method according to claim 7 , wherein the imaging is 3-dimensional imaging.
9. The method according to claim 7 , wherein the imaging is an imaging procedure of the uterine cavity.
10. The method according to claim 9 , wherein the imaging procedure comprises ultra-sound imaging.
11. A method for enhancing contrast of an image of a body cavity, comprising the step of introducing once 1-10 ml of an echo-lucent image enhancing composition according to claim 1 into the body cavity.
12. A high contrast image of a body cavity, wherein the high contrast image is a 3-dimensional image obtained by the method of claim 11 .
13. The method according to claim 9 , wherein the imaging procedure is sonohysterography.
14. A method for enhancing contrast of an image of a body cavity, comprising the step of introducing once 3-5 ml of an echo-lucent image enhancing composition according to claim 1 into the body cavity.