IP Library Granted Patent US 9,198,956
Granted Patent B2
US 9,198,956 · App. 14/665,559 · Granted Dec 1, 2015

Treating liver diseases

Inventors: Nicholas F. LaRusso (Rochester, MN); Tetyana V. Masyuk (Rochester, MN); Melissa Muff-Luett (North Liberty, IA)
Assignee: Mayo Foundation for Medical Education and Research
A61K38/31
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Quick Facts
Patent No.
US 9,198,956
App. No.
14/665,559
Granted
Dec 1, 2015
Kind
B2
Abstract

This document provides methods and materials related to treating liver conditions. For example, the methods and materials relating to the use of cAMP inhibitors to treat liver conditions are provided.

Claims (7)

1. A method for inhibiting cyst growth, said method comprising:

(a) identifying liver tissue comprising a liver cyst, and

(b) contacting said liver cyst with a somatostatin analog under conditions wherein the growth rate of said liver cyst is reduced as compared to the growth rate of a comparable liver cyst not contacted with said somatostatin analog.

2. The method of claim 1 , wherein said somatostatin analog is octreotide.

3. The method of claim 1 , wherein said somatostatin analog is lanreotid.

4. The method of claim 1 , wherein said somatostatin analog is vapreotide.

5. The method of claim 1 , wherein said liver tissue is human liver tissue.

Assignments (2)
CONFIRMATORY LICENSE Recorded Jun 22, 2016
From: MAYO CLINIC ROCHESTER
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 039115/0039 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 26, 2015
From: LARUSSO, NICHOLAS F.; MASYUK, TETYANA V.; MUFF-LUETT, MELISSA
To: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
Reel/Frame 035911/0893 →
Continuity (4)
Continuation 13533257 · Jun 26, 2012
Continuation 11915107
Provisional Application 60683617 · May 23, 2005
Related Publication 20150258179A1 · Sep 17, 2015