IP Library Granted Patent US 10,629,303
Granted Patent B2
US 10,629,303 · App. 14/672,208 · Granted Apr 21, 2020

Systems and methods for determination of patient true state for personalized medicine

Inventors: Darren Matthew Schulte (San Francisco, CA); John O. Schneider (Los Gatos, CA); Vishnuvyas Sethumadhavan (Mountain View, CA); Robert Derward Rogers (Pleasanton, CA)
Assignee: APIXIO, INC.
G16H50/20G06F19/00G06Q50/24G16H50/50G16H10/60G16H40/20
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Quick Facts
Patent No.
US 10,629,303
App. No.
14/672,208
Granted
Apr 21, 2020
Kind
B2
Abstract

Systems and methods for personalizing medicine utilizing the true state of the patient are provided. A number of medical records for a patient are subjected to predictive modeling for various conditions (known as patient ‘true state’). The patient personal information, previous care, and true state may be provided into a state machine in order to determine the resources needed for the patient. The medical resources may be any of laboratory services, diagnostics, therapies and medications. Using the true state information, and number of activities may be performed for the patient based upon the patient's needs. These activities include scheduling lab or diagnostic procedures in advance of an appointment, filling in documentation gaps, identifying items that require additional documentation using the true state, and tracking follow-up. It may also be beneficial to validate the true state.

Claims (35)

1. In a health information management system, a method for personalizing medical care, the method comprising:

receiving a plurality of medical records for a patient;

identifying terms by cross referencing language nodes in the plurality of medical records against a wiki-like database;

identifying medical concepts through machine learned relational clustering of the terms:

inferring a true state for the patient using a processor by applying a predictive model to the medical concepts, wherein the true state is a condition of the patient;

identifying medical resources for the patient using a state machine based upon the true state, the patient's condition and care already received;

scheduling the medical resources for the patient; and

aggregating the true state of a plurality of patients for at least one of estimating actuarial risks for price determination, tracking physician performance, and profiling a provider.

2. The method of claim 1 further comprising generating a confidence level for the inferred true state.

3. The method of claim 1 wherein the medical resources include any of laboratory services, diagnostics, therapies and medications.

4. The method of claim 1 further comprising scheduling lab or diagnostic procedures in advance of an appointment based upon the true state data.

5. The method of claim 1 further comprising filling documentation gaps using the true state.

6. The method of claim 1 further comprising identifying items that require additional documentation using the true state.

7. The method of claim 1 further comprising tracking follow-up.

8. The method of claim 2 further comprising validating the true state.

9. The method of claim 8 wherein the validation updates the predictive model and updates the confidence level for the inferred true state.

10. The method of claim 8 further comprising optimizing routing of evidence for validation based upon greatest impact the evidence has on the true state inference.

11. A health information management system for personalizing medical care comprising:

a records database configured to receive a plurality of medical records for a patient; and

a first pass analyzer including a processor configured to:

identify terms by cross referencing language nodes in the plurality of medical records against a wiki-like database;

identify medical concepts through machine learned relational clustering of the terms;

infer a true state for the patient by applying a predictive model to the medical concepts; and

identify medical resources for the patient using a state machine based upon the true state, the patient's condition and care already received;

schedule the medical resources for the patient; and

aggregate the true state of a plurality of patients for at least one of estimating actuarial risks for price determination, tracking physician performance, and profiling a provider.

12. The system of claim 11 wherein the first pass analyzer is further configured to generate a confidence level for the inferred true state.

13. The system of claim 11 wherein the medical resources include any of laboratory services, diagnostics, therapies and medications.

14. The system of claim 11 wherein the first pass analyzer is further configured to schedule lab or diagnostic procedures in advance of an appointment based upon the true state data.

15. The system of claim 11 wherein the first pass analyzer is further configured to fill documentation gaps using the true state.

16. The system of claim 11 wherein the first pass analyzer is further configured to identify items that require additional documentation using the true state.

17. The system of claim 11 wherein the first pass analyzer is further configured to track follow-up.

18. The system of claim 12 further comprising a validation system configured to validate the true state.

19. The system of claim 18 wherein the validation system updates the predictive model and updates the confidence level for the inferred true state.

20. The system of claim 18 further comprising a routing optimizer configured to optimizing routing of evidence for validation based upon greatest impact the evidence has on the true state inference.

Assignments (5)
CORRECTIVE ASSIGNMENT TO CORRECT THE THE NAME OF THE ASSIGNEE PREVIOUSLY RECORDED AT REEL: 40510 FRAME: 256. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Dec 11, 2024
From: SCHULTE, DARREN MATTHEW; SCHNEIDER, JOHN O.; SETHUMADHAVAN, VISHNUVYAS; ROGERS, ROBERT DERWARD
To: APIXIO INC.
Reel/Frame 069587/0577 →
RELEASE OF SECURITY INTEREST Recorded Aug 30, 2024
From: CHURCHILL AGENCY SERVICES LLC
To: APIXIO, LLC (F/K/A APIXIO INC.)
Reel/Frame 068453/0713 →
ENTITY CONVERSION Recorded Jul 12, 2023
From: APIXIO INC.
To: APIXIO, LLC
Reel/Frame 064259/0006 →
SECURITY INTEREST Recorded Jun 13, 2023
From: APIXIO INC.
To: CHURCHILL AGENCY SERVICES LLC
Reel/Frame 063928/0847 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 2, 2016
From: SCHULTE, DARREN MATTHEW; SCHNEIDER, JOHN O.; SETHUMADHAVAN, VISHNUVYAS; ROGERS, ROBERT DERWARD
To: APIXIO, INC.
Reel/Frame 040510/0256 →
Continuity (8)
Continuation In Part 14538798 · Nov 11, 2014
Continuation In Part 13656652 · Oct 19, 2012
Continuation In Part 14672208
Continuation In Part 14498594 · Sep 26, 2014
Provisional Application 62059139 · Oct 2, 2014
Provisional Application 61682217 · Aug 11, 2012
Provisional Application 61883967 · Sep 27, 2013
Related Publication 20150269337A1 · Sep 24, 2015
Cited By (1)
US 12,217,839