IP Library Granted Patent US 10,143,384
Granted Patent B2
US 10,143,384 · App. 14/677,905 · Granted Dec 4, 2018

Systems and methods for accelerated imaging using variable density sampling and compressed sensing with parallel imaging

Inventors: Xiao Chen (Charlottesville, VA); Frederick H. Epstein (Charlottesville, VA); Yang Yang (Charlottesville, VA); Michael Salerno (Charlottesville, VA); Craig H. Meyer (Charlottesville, VA)
Assignee: University of Virginia Patent Foundation
A61B5/02A61B5/0044A61B5/055G01R33/5611A61B5/0042G01R33/4826G01R33/546G01R33/5608
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Quick Facts
Patent No.
US 10,143,384
App. No.
14/677,905
Granted
Dec 4, 2018
Kind
B2
Abstract

Some aspects of the present disclosure relate to accelerated imaging using variable-density sampling and compressed sensing with parallel imaging. In one embodiment, a method includes acquiring magnetic resonance data associated with a physiological activity in an area of interest of a subject. The acquiring includes performing accelerated variable-density sampling with phase-contrast displacement encoding. The method also includes reconstructing, from the acquired magnetic resonance data, images corresponding to the physiological activity in the area of interest. The reconstructing includes performing parallel imaging and compressed sensing.

Claims (24)

1. A method for accelerated imaging of an area of interest of a subject, comprising:

acquiring magnetic resonance data associated with a physiological activity in an area of interest of a subject, wherein the acquiring comprises performing accelerated variable-density sampling with phase-contrast displacement encoding; and

reconstructing, from the acquired magnetic resonance data, images corresponding to the physiological activity in the area of interest, wherein the reconstructing comprises performing parallel imaging and compressed sensing.

2. The method of claim 1 , wherein the variable-density sampling comprises variable-density spiral sampling.

3. The method of claim 1 , wherein the phase-contrast displacement encoding comprises cine displacement encoding with stimulated echoes (DENSE).

4. The method of claim 1 , wherein the parallel imaging comprises combining multi-channel parallel imaging data using sensitivity maps calculated from temporally-averaged data.

5. The method of claim 1 , wherein the compressed sensing comprises regional-sparsity based compressed sensing.

6. The method of claim 1 , wherein the compressed sensing comprises performing motion-guided compressed sensing functions wherein three-dimensional images from the parallel imaging are divided into cubes that are motion-tracked over time and low-rank sparsity is exploited inside the motion-tracked cubes to remove artifacts.

7. A system for accelerated imaging of an area of interest of a subject, comprising:

a magnetic resonance imaging (MRI) device configured to acquire magnetic resonance data associated with a physiological activity in an area of interest of a subject, wherein the acquiring comprises performing, using the MRI device, accelerated variable-density sampling with phase-contrast displacement encoding; and

an image processing device coupled to the MM device and configured to reconstruct, from the acquired magnetic resonance data, images corresponding to the physiological activity in the area of interest, wherein the reconstructing comprises performing parallel imaging and compressed sensing.

8. The system of claim 7 , wherein the variable-density sampling comprises variable-density spiral sampling.

9. The system of claim 7 , wherein the phase-contrast displacement encoding comprises cine displacement encoding with stimulated echoes (DENSE).

10. The system of claim 7 , wherein the parallel imaging comprises combining multi-channel parallel imaging data using sensitivity maps calculated from temporally-averaged data.

11. The system of claim 7 , wherein the compressed sensing comprises regional-sparsity based compressed sensing.

12. The system of claim 7 , wherein the compressed sensing comprises performing motion-guided compressed sensing functions wherein three-dimensional images from the parallel imaging are divided into cubes that are motion-tracked over time and low-rank sparsity is exploited inside the motion-tracked cubes to remove artifacts.

13. A non-transitory computer-readable medium storing instructions that, when executed by one or more processors, cause a system to perform functions for accelerated imaging of an area of interest of a subject, wherein the functions performed include:

acquiring magnetic resonance data associated with a physiological activity in an area of interest of a subject, wherein the acquiring comprises performing accelerated variable-density sampling with phase-contrast displacement encoding; and

reconstructing, from the acquired magnetic resonance data, images corresponding to the physiological activity in the area of interest, wherein the reconstructing comprises performing parallel imaging and compressed sensing.

14. The computer-readable medium of claim 13 , wherein the variable-density sampling comprises variable-density spiral sampling.

15. The computer-readable medium of claim 13 , wherein the phase-contrast displacement encoding comprises cine displacement encoding with stimulated echoes (DENSE).

16. The computer-readable medium of claim 13 , wherein the parallel imaging comprises combining multi-channel parallel imaging data using sensitivity maps calculated from temporally-averaged data.

17. The computer-readable medium of claim 13 , wherein the compressed sensing comprises regional-sparsity based compressed sensing.

18. The computer-readable medium of claim 13 , wherein the compressed sensing comprises performing motion-guided compressed sensing functions wherein three-dimensional images from the parallel imaging are divided into cubes that are motion-tracked over time and low-rank sparsity is exploited inside the motion-tracked cubes to remove artifacts.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 1, 2017
From: CHEN, XIAO; EPSTEIN, FREDERICK H; YANG, YANG; SALERNO, MICHAEL; MEYER, CRAIG H
To: UNIVERSITY OF VIRGINIA
Reel/Frame 043157/0125 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 1, 2017
From: UNIVERSITY OF VIRGINIA
To: UNIVERSITY OF VIRGINIA PATENT FOUNDATION
Reel/Frame 043157/0322 →
CONFIRMATORY LICENSE Recorded Jul 12, 2016
From: UNIVERSITY OF VIRGINIA
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 039309/0117 →
Continuity (2)
Provisional Application 61974255 · Apr 2, 2014
Related Publication 20150285889A1 · Oct 8, 2015
Cited By (4)
US 12,694,518 US 12,716,972 US 12,725,709 US 12,730,171