IP Library Granted Patent US 10,369,385
Granted Patent B2
US 10,369,385 · App. 14/686,455 · Granted Aug 6, 2019

Quantitative MRI measurements near metal objects

Inventors: Hans Weber (Menlo Park, CA); Daehyun Yoon (Palo Alto, CA); Valentina Taviani (Palo Alto, CA); Brian A. Hargreaves (Menlo Park, CA)
Assignee: The Board of Trustees of the Leland Stanford Junior University
A61N7/02A61B5/055A61B18/12A61N1/403G01R33/4804G01R33/50G01R33/56527A61B5/062
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Quick Facts
Patent No.
US 10,369,385
App. No.
14/686,455
Granted
Aug 6, 2019
Kind
B2
Abstract

A method for providing at least one measurement by a magnetic resonance imaging (MRI) system of a tissue property or underlying tissue property in a region sufficiently close to a metal object, so that the metal object induces artifacts is provided. At least one magnetic resonance imaging signal from the region is acquired through the MRI system. The acquired at least one MRI signal is processed to correct for artifacts induced by the metal object. At least one tissue property or underlying tissue property measurement is extracted from the processed at least one MRI signal.

Claims (40)

1. A method for providing at least one measurement by an MRI system of a tissue property or underlying tissue property in a region sufficiently close to a metal object, so that the metal object induces artifacts, comprising:

acquiring through the magnetic resonance imaging (MRI) system at least one magnetic resonance imaging signal from the region, wherein the acquiring at least one MRI signal compensates for the artifacts induced by the metal object, wherein the acquiring at least one MRI signal comprises acquiring a plurality of MRI signals from the region, and wherein the acquiring uses a multispectral imaging and wherein the acquiring uses a spatially selective inversion pulse matched to excitation;

processing the acquired at least one MRI signal to correct for artifacts induced by the metal object;

extracting at least one tissue property and underlying tissue property measurement by comparing the plurality of MRI signals;

measuring a variation in the at least one tissue property; and

using the variation in the at least one tissue property to determine the underlying tissue property measurement, which is temperature.

2. The method, as recited in claim 1 , further comprising using the measured tissue property to determine the at least one underlying tissue property.

3. The method, as recited in claim 1 , wherein the acquiring of MRI signals is a 2D acquisition.

4. The method, as recited in claim 3 , wherein the tissue property is at least one of T 1 , T 2 , or proton density.

5. The method, as recited in claim 1 , further comprising

providing thermal therapy to the region; and

using the measured temperature to control the thermal therapy device.

6. The method, as recited in claim 1 , wherein the temperature measurement is an absolute temperature measurement.

7. The method, as recited in claim 1 , wherein the temperature measurement is a relative temperature measurement.

8. The method, as recited in claim 1 , wherein the acquiring at least one MRI signal is used to determine a relative distribution of the underlying tissue property.

9. The method, as recited in claim 1 , wherein the acquiring at least one MRI signal comprises acquiring a plurality of MRI signals from the region, and wherein the method further comprises comparing the plurality of MRI signals to measure a relative change of the underlying tissue property.

10. A method for providing a thermal therapy treatment using an MRI system and a thermal therapy device in a region sufficiently close to a metal object, so that the metal object induces artifacts, comprising:

heating the region using the thermal therapy device;

acquiring through the MRI system at least one MRI signal from the region, wherein the acquiring uses a multispectral imaging and wherein the acquiring uses a spatially selective inversion pulse matched to excitation;

processing the acquired at least one MRI signal to correct for artifacts induced by the metal object;

extracting temperature from the processed at least one MRI signal; and

changing the heating of the region based on the extracted temperature.

11. A system for providing thermal therapy treatment to a region sufficiently close to a metal object, so that the metal object induces artifacts, comprising:

a thermal therapy device for providing heat to the region;

a MRI system; and

a controller comprising:

a central processing unit; and

tangible computer readable media, comprising:

computer readable code for heating the region using the thermal therapy device;

computer readable code for acquiring through the MRI system at least one MRI signal from the region, wherein the acquiring uses a multispectral imaging and wherein the acquiring uses a spatially selective inversion pulse matched to excitation;

computer readable code for processing the acquired at least one MRI signal to correct for artifacts induced by the metal object;

computer readable code for extracting temperature from the processed at least one MRI signal; and

computer readable code changing the heating of the region based on the extracted temperature.

12. The system, as recited in claim 11 , wherein the computer readable code for acquiring through the MRI system at least one MRI signal from the region magnetic resonance imaging system uses a two dimensional multispectral imaging acquisition.

13. The system, as recited in claim 12 , wherein the computer readable code for processing at least one MRI signal to correct for artifacts induced by the metal objects corrects for signal loss artifacts and pile-up artifacts induced by the metal objects.

14. The method, as recited in claim 10 , wherein the acquiring through the MRI system uses a two dimensional multispectral imaging acquisition.

15. The method, as recited in claim 14 , wherein the processing the acquired at least one MRI signal to correct for artifacts induced by the metal objects corrects for signal loss artifacts and pile-up artifacts induced by the metal objects.

16. The method, as recited in claim 1 , wherein the acquiring through the magnetic resonance imaging system uses a two dimensional multispectral imaging acquisition.

17. The method, as recited in claim 16 , wherein the processing the acquired at least one MRI signal to correct for artifacts induced by the metal objects corrects for signal loss artifacts and pile-up artifacts induced by the metal objects.

18. The method, as recited in claim 16 , wherein the two dimensional multispectral imaging acquisition comprises reversing a selection gradient between excitation and refocusing pulses resulting in an excitation of finite spectral and spatial regions to provide reduced distortion near the metal object.

Assignments (2)
CONFIRMATORY LICENSE Recorded Mar 1, 2018
From: STANFORD UNIVERSITY
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 045474/0817 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 29, 2015
From: WEBER, HANS; YOON, DAEHYUN; TAVIANI, VALENTINA; HARGREAVES, BRIAN A.
To: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
Reel/Frame 035547/0367 →
Continuity (1)
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