Patent Application
App. No. 14/692,461
TECHNOLOGY FOR PREPARATION OF MACROMOLECULAR MICROSPHERES
Loading inventors, assignments & file history…
Abstract
Microspheres are produced by contacting an aqueous solution of a protein or other macromolecule with an organic solvent and a counterion, and chilling the solution. The microspheres are useful for preparing pharmaceuticals of defined dimensions.
Claims (5)
1 . A method of making a protein-based composition, comprising:
a) adding a counterion to a solution containing the protein in an aqueous solvent;
b) adding an organic solvent to the solution; and
c) gradually cooling the solution to a temperature below about 25° C., whereby a composition containing microparticles comprising the protein is formed, wherein steps a), b) and c) are performed simultaneously, sequentially, intermittently, or in any order.
2 .- 141 . (canceled)
Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Apr 22, 2015
From: MALAKHOV, MICHAEL P.; FANG, FANG
To: NEXBIO, INC.
Reel/Frame 035465/0753 →
CHANGE OF NAME
Recorded Apr 22, 2015
From: NEXBIO, INCORPORATED
To: ANSUN BIOPHARMA, INC.
Reel/Frame 035475/0860 →