IP Library Granted Patent US 10,675,145
Granted Patent B2
US 10,675,145 · App. 14/692,960 · Granted Jun 9, 2020

Corneal implants

Inventor: Yichieh Shiuey (San Jose, CA)
Assignee: Keramed, Inc.
A61F2/1451A61F2/142A61F2/1453A61F2/15A61F2002/0081A61F2002/0086A61F2002/0091A61F2210/0014A61F2210/0076A61F2220/0033A61F2230/0006A61F2230/0093A61F2250/0018A61F2250/0026A61F2250/0036A61F2250/0053
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Quick Facts
Patent No.
US 10,675,145
App. No.
14/692,960
Granted
Jun 9, 2020
Kind
B2
Abstract

Reversibly deformable corneal implants for replacing excised corneal tissue, the implants including an optical portion and an anchoring portion having different mechanical properties from each other.

Claims (53)

1. A corneal implant comprising:

an artificial cornea for replacing corneal tissue;

said artificial cornea comprising a relaxed state and a deformed state, and being reversibly deformable such that said artificial cornea can be implanted in said deformed state into an eye through an opening that is less than the width of the artificial cornea in said relaxed state, and, upon implantation into said eye, can return in said eye to said relaxed state without said artificial cornea breaking, and such that said artificial cornea is automatically reversible to said relaxed state;

said artificial cornea comprising a vertical axis;

said artificial cornea further comprising a center optic, said center optic being an optical portion in the center of said artificial cornea, wherein at approximately 25 degrees Celsius said optical portion has a Young's modulus parallel to said vertical axis in a range from approximately 300 GPa to approximately 600 GPa;

said artificial cornea further comprising an annular rim with cutouts surrounding said optical portion.

2. A corneal implant as claimed in claim 1 , wherein said annular rim comprises a Young's modulus that differ from said center optic.

3. A corneal implant as claimed in claim 2 , wherein at approximately 5° C. said annular rim comprises a Young's modulus in a range from approximately 20 GPa to about 40 GPa.

4. A corneal implant as claimed in claim 1 , wherein said annular rim is made from a different material than said center optic.

5. A corneal implant as claimed in claim 1 , wherein said artificial cornea is monolithic.

6. A corneal implant as claimed in claim 1 , wherein said cutouts are oblong.

7. A corneal implant comprising:

an artificial cornea for replacing corneal tissue;

said artificial cornea comprising a relaxed state and a deformed state, and being reversibly deformable such that said artificial cornea can be implanted in said deformed state into an eye through an opening that is less than the width of the artificial cornea in said relaxed state, and, upon implantation into said eye, can return in said eye to said relaxed state without said artificial cornea breaking, and such that said artificial cornea is automatically reversible to said relaxed state;

said artificial cornea comprising a vertical axis;

said artificial cornea further comprising a center optic, said center optic being an optical portion in the center of said artificial cornea, wherein at approximately 25 degrees Celsius said optical portion has a Young's modulus parallel to said vertical axis in a range from approximately 300 GPa to approximately 600 GPa;

said artificial cornea further comprising a first pair of connecting elements projecting from said center optic;

said artificial cornea further comprising a first annular rim extending between said first pair of connecting elements;

said artificial cornea further comprising a first hollow section, said first hollow section being located between said first pair of connecting elements, and being located between said first annular rim and said center optic;

said artificial cornea further comprising a second pair of connecting elements projecting from said center optic;

said artificial cornea further comprising a second annular rim extending between said second pair of connecting elements;

said artificial cornea further comprising a second hollow section, said second hollow section being located between said second pair of connecting elements, and being located between said second annular rim and said center optic.

8. A corneal implant as claimed in claim 7 , further comprising a gap positioned laterally between said first annular rim and said second annular rim.

9. A corneal implant as claimed in claim 7 , said artificial cornea further comprising a third pair of connecting elements projecting from said center optic;

said artificial cornea further comprising a third annular rim extending between said third pair of connecting elements;

said artificial cornea further comprising a third hollow section, said third hollow section being located between said third pair of connecting elements, and being located between said third annular rim and said center optic.

10. A corneal implant as claimed in claim 9 , further comprising a gap positioned laterally between said first annular rim and said second annular rim, and comprising a gap positioned laterally between said second annular rim and said third annular rim, and comprising a gap positioned laterally between said third annular rim and said first annular rim.

11. A corneal implant as claimed in claim 9 , wherein said annular rims comprise the same mechanical properties, and wherein said annular rims comprise mechanical properties that differ from said center optic, such that said annular rims comprise a Young's modulus that differs from said center optic.

12. A corneal implant as claimed in claim 9 , wherein said annular rims are made from the same material, and wherein said annular rims are made from a different material than said center optic.

13. A corneal implant as claimed in claim 9 , wherein said artificial cornea is monolithic.

14. A corneal implant as claimed in claim 7 , wherein said annular rims comprise the same mechanical properties, and wherein said annular rims comprise mechanical properties that differ from said center optic, such that said annular rims comprise a Young's modulus that differs from said center optic.

15. A corneal implant as claimed in claim 14 , wherein at approximately 5° C. said annular rims comprise a Young's modulus in a range from approximately 20 GPa to about 40 GPa.

16. A corneal implant as claimed in claim 7 , wherein said annular rims are made from the same material, and wherein said annular rims are made from a different material than said center optic.

17. A corneal implant as claimed in claim 7 , wherein said artificial cornea is monolithic.

18. A corneal implant comprising:

an artificial cornea for replacing corneal tissue;

said artificial cornea comprising a relaxed state and a deformed state, and being reversibly deformable such that said artificial cornea can be implanted in said deformed state into an eye through an opening that is less than the width of the artificial cornea in said relaxed state, and, upon implantation into said eye, can return in said eye to said relaxed state without said artificial cornea breaking, and such that said artificial cornea is automatically reversible to said relaxed state;

said artificial cornea comprising a vertical axis;

said artificial cornea further comprising a center optic, said center optic being an optical portion in the center of said artificial cornea, wherein at approximately 25 degrees Celsius said optical portion has a Young's modulus parallel to said vertical axis in a range from approximately 300 GPa to approximately 600 GPa;

said artificial cornea further comprising a first pair of connecting elements projecting from said center optic;

said artificial cornea further comprising a first annular rim extending between said first pair of connecting elements;

said artificial cornea further comprising a first hollow section, said first hollow section being located between said first pair of connecting elements, and being located between said first annular rim and said center optic;

said artificial cornea further comprising a second pair of connecting elements projecting from said center optic;

said artificial cornea further comprising a second annular rim extending between said second pair of connecting elements;

said artificial cornea further comprising a second hollow section, said second hollow section being located between said second pair of connecting elements, and being located between said second annular rim and said center optic;

said artificial cornea further comprising a third pair of connecting elements projecting from said center optic;

said artificial cornea further comprising a third annular rim extending between said third pair of connecting elements;

said artificial cornea further comprising a third hollow section, said third hollow section being located between said third pair of connecting elements, and being located between said third annular rim and said center optic;

said artificial cornea further comprising a gap positioned laterally between said first annular rim and said second annular rim, and comprising a gap positioned laterally between said second annular rim and said third annular rim, and comprising a gap positioned laterally between said third annular rim and said first annular rim; and,

wherein said artificial cornea is monolithic.

19. A corneal implant as claimed in claim 18 , wherein said annular rims comprise the same mechanical properties, and wherein said annular rims comprise mechanical properties that differ from said center optic, such that said annular rims comprise a Young's modulus that differs from said center optic.

20. A corneal implant as claimed in claim 19 , wherein at approximately 5° C. said annular rims comprise a Young's modulus in a range from approximately 20 GPa to about 40 GPa.

21. A corneal implant as claimed in claim 18 , wherein said annular rims are made from the same material, and wherein said annular rims are made from a different material than said center optic.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 6, 2015
From: SHIUEY, YICHIEH
To: KERAMED, INC.
Reel/Frame 035577/0512 →
Continuity (3)
Continuation In Part 13979122
Provisional Application 61388386 · Sep 30, 2010
Related Publication 20150223930A1 · Aug 13, 2015
Cited By (1)
US 12,521,230