Granted Patent
B2
US 10,053,486 · App. 14/696,204 · Granted Aug 21, 2018
Preparation of bile acids and intermediates thereof
Inventors:
Achampeta Rathan Prasad (Hyderabad, IN); Roy A. Swaringen, Jr. (Durham, NC); John Gregory Reid (Groton, MA); Robert M. Moriarty (Michiana Shores, IN); Akhila Kumar Sahoo (Hyderabad, IN)
Assignee:
Kythera Biopharmaceuticals, Inc.
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Abstract
Synthetic methods for preparing deoxycholic acid and intermediates thereof are provided.
Claims (5)
1. A composition comprising a compound of formula 1.9
wherein R is alkyl and P is a protecting group, and a hydrogenation catalyst, wherein the hydrogenation catalyst consists of Pd/C.
2. The composition of claim 1 , further comprising a solvent.
3. The composition of claim 2 , wherein the solvent is ethyl acetate.
4. The composition of claim 1 , wherein —OP is —OAc and —CO 2 R is —CO 2 Me.
Assignments (4)
MERGER AND CHANGE OF NAME
Recorded Oct 8, 2019
From: KYTHERA BIOPHARMACEUTICALS, LLC; ALLERGAN SALES, LLC
To: ALLERGAN SALES, LLC
Reel/Frame 050656/0475 →
CHANGE OF NAME
Recorded Oct 4, 2019
From: KYTHERA BIOPHARMACEUTICALS, INC.
To: KYTHERA BIOPHARMACEUTICALS, LLC
Reel/Frame 050638/0069 →
CORRECTIVE ASSIGNMENT TO CORRECT THE NAME OF THE ASSIGNEE PREVIOUSLY RECORDED AT REEL: 036015 FRAME: 0725. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT.
Recorded Aug 18, 2015
From: PRASAD, ACHAMPETA RATHAN; SWARINGEN, ROY A., JR.; REID, JOHN GREGORY; MORIARTY, ROBERT M.; SAHOO, AKHILA KUMAR
To: KYTHERA BIOPHARMACEUTICALS, INC.
Reel/Frame 036381/0349 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Jul 7, 2015
From: PRASAD, ACHAMPETA RATHAN; SWARINGEN, ROY A., JR.; REID, JOHN GREGORY; MORIARTY, ROBERT M.; SAHOO, AKHILA KUMAR
To: KYHTERA BIOPHARMACEUTICALS, INC.
Reel/Frame 036015/0725 →
Priority Claims (1)
GB 0807615.0
· Apr 25, 2008
· national
Continuity (5)