Targeting cancer with metabolic therapy and hyperbaric oxygen
A method of treating cancer using ketogenic diet, while concurrently subjecting the patient to a hyperbaric, oxygen-enriched environment. Optionally, the hyperbaric, oxygen-enriched environment is 100% oxygen at 2.5 ATA absolute. The treatment may further include administering at least 10% ketone supplementation, such as acetoacetate, adenosine monophosphate kinase, 1,3-butanediol, or ketone ester, to the patient.
1. A method of reducing metastasis in cancer, comprising:
administering to an animal with a metastatic cancer a therapeutically effective amount of acetoacetate, 1,3-butanediol acetoacetate monoester, 1,3-butanediol acetoacetate diester, R,S-1,3-butanediol-diacetoacetate ester, R-1,3-butanediol diacetoacetate ester, or a combination thereof.
2. The method of claim 1 , further comprising subjecting the animal to a hyperbaric, oxygen-enriched environment.
3. The method of claim 2 , wherein the hyperbaric, oxygen-enriched environment is 100% oxygen.
4. The method of claim 3 , wherein the hyperbaric, oxygen-enriched environment is at 2.5 ATA absolute.
5. The method of claim 3 , wherein the animal is subjected to the hyperbaric, oxygen-enriched environment for 90 minutes three times a week.
6. The method of claim 1 , wherein the acetoacetate, 1,3-butanediol acetoacetate monoester, 1,3-butanediol acetoacetate diester, R,S-1,3-butanediol-diacetoacetate ester, R-1,3-butanediol diacetoacetate ester, or a combination thereof is administered at 10 g/kg of body weight.