Decellularized adipose tissue

1. A decellularized adipose tissue comprising an extracellular matrix including fibrous collagen and network-type collagen including collagen type IV with basement membrane organization, with well-preserved three-dimensional architecture.

2. The decellularized adipose tissue of claim 1 , wherein the decellularized adipose tissue is substantially devoid of intact adipose cells.

3. The decellularized adipose tissue of claim 1 , wherein the decellularized adipose tissue is substantially free of immunogenic components.

4. The decellularized adipose tissue of claim 1 , including one or more of proteoglycan, glycoprotein, glycosaminoglycan, laminin, or fibronectin.

5. The decellularized adipose tissue of claim 1 , for use as a cell culture substrate.

6. The decellularized adipose tissue of claim 5 , wherein the cell culture substrate is for cell expansion and/or cell differentiation and/or for the production of bioproducts comprising tissue and one or more proteins.

7. The decellularized adipose tissue of claim 1 , comprising at least one additive selected from seeded cells, a biomaterial, a pharmaceutical agent, a hormone, and a growth factor.

8. The decellularized adipose tissue of claim 1 , comprising at least one additive selected from a hydrogel and a derivative of one or more of collagen, gelatin, hyaluronan, chondroitin sulphate, chitosan, alginate, silk, fibrin, protein, proteoglycan, glycosaminoglycan, and polysaccharide.

9. The decellularized adipose tissue of claim 1 , comprising a hydrogel based on one or more of poly(ethylene glycol) (PEG), polyethylene, polyurethane, polylactic acid (PLA), polyglycolic acid (PGA), and polylactic co-glycolic acid (PLGA.

10. The decellularized adipose tissue of claim 1 , wherein the decellularized adipose tissue is digested and solubilized into a liquid.

11. A bioscaffold prepared from the decellularized adipose tissue of claim 1 .

12. The bioscaffold of claim 11 , for use in a surgical procedure.

13. The bioscaffold of claim 12 , wherein the surgical procedure is general surgery, reconstructive surgery, cosmetic surgery, cardiac surgery, orthopaedic surgery, neurosurgery, or urological or gynaecological surgery.

14. The bioscaffold of claim 11 , wherein the bioscaffold is used for wound healing applications.

15. The bioscaffold of claim 11 , wherein the bioscaffold is used as a hemostatic agent.

16. The bioscaffold of claim 11 , comprising one or more materials selected from decellularized extracellular matrix derived from a non-adipose tissue, a synthetic material, a pharmaceutical composition, a hormone, and a growth factor.

17. The bioscaffold of claim 11 , wherein the bioscaffold is autologous or allogenic.

18. The bioscaffold of claim 11 , wherein the bioscaffold is xenogenic.

19. A scaffold prepared from the decellularized adipose tissue of claim 10 .

20. A coating prepared from the decellularized adipose tissue of claim 10 .

21. The coating of claim 20 , wherein the coating is cross-linked.

22. A microcarrier bead prepared from the decellularized adipose tissue of claim 10 .

23. A microcarrier bead including the coating of claim 20 .

24. The microcarrier bead of claim 22 , for use as a cell and/or drug and/or growth factor delivery vehicle.

25. The microcarrier bead of claim 22 , for use as a small volume-bulking agent in cosmetic or reconstructive surgery.

26. The microcarrier bead of claim 22 , for use in fabrication of a composite bioscaffold with decellularized adipose tissue.

27. The microcarrier bead of claim 22 , wherein the microcarrier bead is cross-linked.

28. The microcarrier bead of claim 22 , wherein the microcarrier bead is porous.

29. A particle prepared from the decellularized adipose tissue of claim 1 .

30. A particle including the coating of claim 20 .