IP Library › Granted Patent US 9,655,565
Granted Patent B2
US 9,655,565 · App. 14/720,668 · Granted May 23, 2017

Systems and methods for dynamically and intelligently monitoring a host's glycemic condition after an alert is triggered

Inventors: Hari Hampapuram (Carlsbad, CA); Anna Leigh Rack-Gomer (Cardiff by the Sea, CA); Naresh C. Bhavaraju (San Diego, CA); Apurv Ullas Kamath (San Diego, CA); Claudio Cobelli (Padua, IT); Giovanni Sparacino (Padua, IT); Andrea Facchinetti (Padua, IT); Chiara Zecchin (Pernumia, IT)
Assignee: DexCom, Inc.
A61B5/7275A61B5/0004A61B5/14532A61B5/746A61B5/002A61B5/0022
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Quick Facts
Patent No.
US 9,655,565
App. No.
14/720,668
Granted
May 23, 2017
Kind
B2
Abstract

Systems and methods for providing sensitive and specific alarms indicative of glycemic condition are provided herein. In an embodiment, a method of processing sensor data by a continuous analyte sensor includes: evaluating sensor data using a first function to determine whether a real time glucose value meets a first threshold; evaluating sensor data using a second function to determine whether a predicted glucose value meets a second threshold; activating a hypoglycemic indicator if either the first threshold is met or if the second threshold is predicted to be met; and providing an output based on the activated hypoglycemic indicator.

Claims (34)

1. A method of avoiding unnecessary hyperglycemic alerts, the method comprising:

initially activating a first alert state based on a first criteria associated with a hyperglycemic condition of a host;

waiting a time period before providing an output associated with the first alert state;

actively monitoring, by a processor module, data associated with the host's hyperglycemic condition during the waiting time period;

providing an output associated with the first alert state after the waiting time period based on the data associated with the host's hyperglycemic condition meeting a second criteria, wherein the first criteria includes a first glucose level threshold and the second criteria includes a second glucose level threshold higher than the first glucose level threshold;

not providing the output associated with the first alert state after the waiting time period based on the data associated with the host's hyperglycemic condition not meeting the second criteria; and

transitioning from the first alert state to an inactive alert state based on the data associated with the host's hyperglycemic condition meeting a third criteria, wherein the third criteria includes a third glucose level threshold lower than the first glucose level threshold.

2. The method of claim 1 , wherein the actively monitoring comprises determining an average glucose over a window of time.

3. The method of claim 1 , wherein the actively monitoring comprises determining an amplitude and/or direction of rate of change.

4. The method of claim 1 , wherein the actively monitoring comprises determining an amplitude and/or direction of rate of acceleration.

5. The method of claim 1 , wherein the actively monitoring comprises evaluating insulin information.

6. The method of claim 1 , wherein the actively monitoring comprises evaluating meal information or timing.

7. The method of claim 1 , wherein the waiting time period is user selectable.

8. A system for processing data, the system comprising:

a continuous analyte sensor configured to be implanted within a body; and

sensor electronics configured to receive and process sensor data output by the sensor, the sensor electronics including a processor configured to:

initially activate a first alert state based on a first criteria associated with a hyperglycemic condition of a host,

wait a time period before providing an output associated with the first alert state,

actively monitor data associated with the host's hyperglycemic condition during the waiting time period,

provide an output associated with the first alert state after the waiting time period based on the data associated with the host's hyperglycemic condition meeting a second criteria, wherein the first criteria includes a first glucose level threshold and the second criteria includes a second glucose level threshold higher than the first glucose level threshold, and

transition from the first alert state to an inactive alert state based on the data associated with the host's hyperglycemic condition meeting a third criteria, wherein the third criteria includes a third glucose level threshold lower than the first glucose level threshold.

9. The system of claim 8 , wherein the actively monitoring comprises determining an average glucose over a window of time.

10. The system of claim 8 , wherein the actively monitoring comprises determining an amplitude and/or direction of rate of change.

11. The system of claim 8 , wherein the actively monitoring comprises determining an amplitude and/or direction of rate of acceleration.

12. The system of claim 8 , wherein the waiting time period is user selectable.

13. The method of claim 1 , further comprising transitioning from the first alert state to an active alert state during the waiting time period based on the data associated with the host's hyperglycemic condition meeting the second criteria.

14. A method of avoiding unnecessary hyperglycemic alerts, the method comprising:

initially activating a first alert state based on a first criteria associated with a hyperglycemic condition of a host;

waiting a time period before providing an output associated with the first alert state;

actively monitoring, by a processor module, data associated with the host's hyperglycemic condition during the waiting time period;

providing an output associated with the first alert state after the waiting time period based on the data associated with the host's hyperglycemic condition meeting a second criteria, wherein the first criteria includes a first glucose level threshold and the second criteria includes a second glucose level threshold higher than the first glucose level threshold;

not providing the output associated with the first alert state after the waiting time period based on the data associated with the host's hyperglycemic condition not meeting the second criteria,

wherein the second glucose level threshold is a current glucose level plus a predetermined margin more than the first glucose level threshold.

15. The method of claim 14 , wherein the predetermined margin includes a range of glucose levels between 10 mg/dL and 80 mg/dL.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 12, 2015
From: BHAVARAJU, NARESH C.; HAMPAPURAM, HARI; KAMATH, APURV ULLAS; RACK-GOMER, ANNA LEIGH
To: DEXCOM, INC.; UNIVERSITA DEGLI STUDI DI PADOVA
Reel/Frame 037022/0858 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 12, 2015
From: COBELLI, CLAUDIO; FACCHINETTI, ANDREA; SPARACINO, GIOVANNI; ZECCHIN, CHIARA
To: DEXCOM, INC.; UNIVERSITA DEGLI STUDI DI PADOVA
Reel/Frame 037022/0946 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 12, 2015
From: UNIVERSITA DEGLI STUDI DI PADOVA
To: DEXCOM, INC.
Reel/Frame 037023/0005 →
Continuity (4)
Continuation 13742841 · Jan 16, 2013
Continuation 13742694 · Jan 16, 2013
Provisional Application 61720286 · Oct 30, 2012
Related Publication 20150250429A1 · Sep 10, 2015