Methods for treating viral infections using hydrogen sulfide donors
View Patent ↗Certain embodiments are directed to methods of treating respiratory infection by administering an H 2 S donor.
1. A method for treating a paramyxovirus viral infection of the respiratory tract of a subject comprising administering an effective amount of a H 2 S donor to the subject.
2. The method of claim 1 , wherein the paramyxovirus is Respiratory Syncytial Virus (RSV), Nipah virus, or human Metapneumovirus (hMPV).
3. The method of claim 1 , wherein the subject is suspected of having a respiratory tract infection.
4. The method of claim 1 , wherein the subject has been diagnosed with a respiratory tract infection.
5. The method of claim 1 , wherein the subject is suspected of being exposed to a paramyxovirus.
6. The method of claim 1 , wherein the H 2 S donor is administered by inhalation or inspiration into the respiratory tract.
7. The method of claim 1 , wherein the H 2 S donor is a slow release H 2 S donor.
8. The method of claim 1 , wherein the slow release H 2 S donor is administered in combination with a fast release H 2 S donor.
9. The method of claim 1 , wherein the H 2 S donor is Gyy4137, ACS67, diallyl trisulfide, NaHS, ATB-343, ATB-337, or AP67.
10. The method of claim 1 , wherein the H 2 S donor is Gyy4137 or AP67.