IP Library › Granted Patent US 10,029,117
Granted Patent B2
US 10,029,117 · App. 14/729,864 · Granted Jul 24, 2018

Systems and methods for interior energy-activation from an exterior source

Inventor: Frederic A. Bourke, Jr. (Greenwich, CT)
Assignee: IMMUNOLIGHT, LLC
A61N5/10A23L3/26A23L3/263A23L5/32A61K41/0057A61K41/0066A61L2/0011A61L2/0047A61L2/082A61L2/10A61L2/16A61N5/062A61N5/0624B01J19/082B01J19/085B01J19/12B01J19/123B01J19/125B01J19/127B01J19/128C02F1/30C02F1/307C02F1/32C02F1/725C08J3/28G21K5/00A61N2005/0661A61N2005/0662A61N2005/1087A61N2005/1089A61N2005/1098B01J2219/0877B01J2219/0879B01J2219/0892B01J2219/1203B82Y20/00C02F1/302C02F1/305C02F2305/10Y02W10/37Y10T156/10
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 10,029,117
App. No.
14/729,864
Filed
Jun 3, 2015
Granted
Jul 24, 2018
Kind
B2
Art Unit
1765
USPC
422/220
Abstract

A method and a system for producing a change in a medium. The method places in a vicinity of the medium at least one energy modulation agent. The method applies an initiation energy to the medium. The initiation energy interacts with the energy modulation agent to directly or indirectly produce the change in the medium. The system includes an initiation energy source configured to apply an initiation energy to the medium to activate the energy modulation agent.

Claims (69)

1. A method for curing an adhesive, comprising:

disposing in contact with an interior surface of a plastic or rubber object an adhesive composition comprising 1) an uncured radiation-curable medium, 2) an energy modulation agent selected from the group consisting of telluride semiconductors, selenide semiconductors, oxide semiconductors, Y 2 O 3 ; ZnSe; Mn, Er ZnSe; Mn; Mn, Yb ZnSe; Mn, Y 2 O 3 :Tb 3+ ; Y 2 O 3 :Tb 3+ , Er 3+ ; CdSe, Y 2 O 3 :Eu 3+ , Y 2 O 3 :Eu 3+ ; BaFBr:Tb 3+ ; and YF 3 :Tb 3+ , and 3) a photo-activated photoinitiator;

applying energy from at least one of x-rays, gamma rays, or an electron beam through the plastic or rubber structure into the composition, wherein the energy interacts with the energy modulation agent and internally generates light inside the uncured radiation-curable medium at the interior surface of the plastic or rubber object and

activating the photoinitiator in the radiation-curable medium with the internally generated light and thereby curing or sterilizing the radiation-curable medium.

2. The method of claim 1 , wherein the object comprises a medical device.

3. The method of claim 1 , wherein disposing comprises disposing at least one of a telluride, a selenide, and an oxide semiconductor as the energy modulation agent.

4. The method of claim 1 , wherein the disposing comprises disposing at least one of Y 2 O 3 ; ZnSe; Mn, Er ZnSe; Mn; Mn, Yb ZnSe; Mn, Y 2 O 3 :Tb 3+ ; Y 2 O 3 :Tb 3+ , Er 3+ ; CdSe, Y 2 O 3 :Eu 3+ , Y 2 O 3 :Eu 3+ ; BaFBr:Tb 3+ ; and YF 3 :Tb 3+ as the energy modulation agent.

5. The method of claim 1 , wherein the activating comprises: activating the photoinitiator with 200-280 nm wavelength ultraviolet light.

6. The method of claim 1 , wherein the activating comprises: activating the photoinitiator with 280-320 nm wavelength ultraviolet light.

7. The method of claim 1 , wherein the activating comprises: activating the photoinitiator with 320-400 nm wavelength ultraviolet light.

8. The method of claim 1 , wherein the activating comprises: activating the photoinitiator with 350-400 nm wavelength ultraviolet light.

9. The method of claim 1 , wherein the photoinitiator comprises at least one of at least one of benzoin, substituted benzoins, Michler's ketone, dialkoxyacetophenones, diethoxyacetophenone, benzophenone, substituted benzophenones, acetophenone, substituted acetophenones, xanthone, substituted xanthones, diethoxyxanthone, chloro-thio-xanthone, azo-bisisobutyronitrile, N-methyl diethanolaminebenzophenone, camphoquinone, peroxyester initiators, non-fluorene-carboxylic acid peroxyesters and mixtures thereof.

10. The method of claim 1 , wherein the photoinitiator comprises a weight percentage of the uncured radiation-curable medium ranging from 0.1% to 10%.

11. The method of claim 1 , wherein the photoinitiator comprises a weight percentage of the uncured radiation-curable medium ranging from 2 to 6%.

12. The method of claim 1 , wherein the uncured radiation-curable medium includes a moisture cure catalyst.

13. A method for curing an adhesive, comprising:

disposing in contact with an interior surface of a plastic or rubber object an adhesive composition comprising 1) an uncured radiation-curable medium comprising a UV-curable silicone, 2) an energy modulation agent selected from the group consisting of telluride semiconductors, selenide semiconductors, oxide semiconductors, Y 2 O 3 ; ZnSe; Mn, Er ZnSe; Mn; Mn, Yb ZnSe; Mn, Y 2 O 3 :Tb 3+ ; Y 2 O 3 :Tb 3+ , Er 3+ ; CdSe, Y 2 O 3 :Eu 3+ , Y 2 O 3 :Eu 3+ ; BaFBr:Tb 3+ ; and YF 3 :Tb 3+ , and 3) a photo-activated photoinitiator;

applying energy from at least one of x-rays, gamma rays, or an electron beam through the plastic or rubber structure into the composition, wherein the energy interacts with the energy modulation agent and internally generates light inside the uncured radiation-curable medium at the interior surface of the plastic or rubber object and

activating the photoinitiator in the radiation-curable medium with the internally generated light and thereby curing or sterilizing the radiation-curable medium.

14. The method of claim 13 , wherein the object comprises a medical device.

15. The method of claim 13 , wherein disposing comprises disposing at least one of a telluride, a selenide, and an oxide semiconductor as the energy modulation agent.

16. The method of claim 13 , wherein the disposing comprises disposing at least one of Y 2 O 3 ; ZnSe; Mn, Er ZnSe; Mn; Mn, Yb ZnSe; Mn, Y 2 O 3 :Tb 3+ ; Y 2 O 3 :Tb 3+ , Er 3+ ; CdSe, Y 2 O 3 :Eu 3+ , Y 2 O 3 :Eu 3+ ; BaFBr:Tb 3+ ; and YF 3 :Tb 3+ as the energy modulation agent.

17. The method of claim 13 , wherein the activating comprises: activating the photoinitiator with 200-280 nm wavelength ultraviolet light.

18. The method of claim 13 , wherein the activating comprises: activating the photoinitiator with 280-320 nm wavelength ultraviolet light.

19. The method of claim 13 , wherein the activating comprises: activating the photoinitiator with 320-400 nm wavelength ultraviolet light.

20. The method of claim 13 , wherein the activating comprises: activating the photoinitiator with 350-400 nm wavelength ultraviolet light.

21. The method of claim 13 , wherein the UV-curable silicone comprises an organopolysiloxane.

22. The method of claim 13 , wherein the UV-curable silicone includes a methacrylate group.

23. The method of claim 13 , wherein the UV-curable silicone includes an acryloxy group.

24. The method of claim 13 , wherein the UV-curable silicone includes at least one of carboxylate, maleate, and cinnamate.

25. The method of claim 13 , wherein the UV-curable silicone includes at least one of trimethylsilyl, dimethylsilyl, phenyldimethylsilyl, vinyldimethylsilyl, trifluoropropyldimethylsilyl, (4-vinylphenyl)dimethylsilyl, (vinylbenzyl)dimethylsilyl, and (vinylphenethyl)dimethylsilyl.

26. The method of claim 13 , wherein the photoinitiator comprises at least one of at least one of benzoin, substituted benzoins, Michler's ketone, dialkoxyacetophenones, diethoxyacetophenone, benzophenone, substituted benzophenones, acetophenone, substituted acetophenones, xanthone, substituted xanthones, diethoxyxanthone, chloro-thio-xanthone, azo-bisisobutyronitrile, N-methyl diethanolaminebenzophenone, camphoquinone, peroxyester initiators, non-fluorene-carboxylic acid peroxyesters and mixtures thereof.

27. The method of claim 13 , wherein the photoinitiator comprises a weight percentage of the uncured radiation-curable medium ranging from 0.1% to 10%.

28. The method of claim 13 , wherein the photoinitiator comprises a weight percentage of the uncured radiation-curable medium ranging from 2 to 6%.

29. The method of claim 13 , wherein the uncured radiation-curable medium includes a moisture cure catalyst.

30. A method for curing an adhesive, comprising:

disposing in contact with an interior surface of a plastic or rubber object an adhesive composition comprising 1) an uncured radiation-curable medium, 2) an energy modulation agent selected from the group consisting of telluride semiconductors, selenide semiconductors, oxide semiconductors, Y 2 O 3 ; ZnSe; Mn, Er ZnSe; Mn; Mn, Yb ZnSe; Mn, Y 2 O 3 :Tb 3+ ; Y 2 O 3 :Tb 3+ , Er 3+ ; CdSe, Y 2 O 3 :Eu 3+ , Y 2 O 3 :Eu 3+ ; BaFBr:Tb 3+ ; and YF 3 :Tb 3+ , and 3) a photo-activated photoinitiator; wherein the plastic or rubber object comprises a medical device;

applying energy from at least one of x-rays, gamma rays, or an electron beam through the plastic or rubber structure into the composition, wherein the energy interacts with the energy modulation agent and internally generates light inside the uncured radiation-curable medium at the interior surface of the plastic or rubber object and

activating the photoinitiator in the radiation-curable medium with the internally generated light and thereby curing or sterilizing the radiation-curable medium.

31. The method of claim 30 , wherein disposing comprises disposing at least one of a telluride, a selenide, and an oxide semiconductor as the energy modulation agent.

32. The method of claim 30 , wherein the disposing comprises disposing at least one of Y 2 O 3 ; ZnSe; Mn, Er ZnSe; Mn; Mn, Yb ZnSe; Mn, Y 2 O 3 :Tb 3+ ; Y 2 O 3 :Tb 3+ , Er 3+ ; CdSe, Y 2 O 3 :Eu 3+ , Y 2 O 3 :Eu 3+ ; BaFBr:Tb 3+ ; and YF 3 :Tb 3+ as the energy modulation agent.

33. The method of claim 30 , wherein the activating comprises: activating the photoinitiator with 200-280 nm wavelength ultraviolet light.

34. The method of claim 30 , wherein the activating comprises: activating the photoinitiator with 280-320 nm wavelength ultraviolet light.

35. The method of claim 30 , wherein the activating comprises: activating the photoinitiator with 320-400 nm wavelength ultraviolet light.

36. The method of claim 30 , wherein the activating comprises: activating the photoinitiator with 350-400 nm wavelength ultraviolet light.

37. The method of claim 30 , wherein the photoinitiator comprises at least one of at least one of benzoin, substituted benzoins, Michler's ketone, dialkoxyacetophenones, diethoxyacetophenone, benzophenone, substituted benzophenones, acetophenone, substituted acetophenones, xanthone, substituted xanthones, diethoxyxanthone, chloro-thio-xanthone, azo-bisisobutyronitrile, N-methyl diethanolaminebenzophenone, camphoquinone, peroxyester initiators, non-fluorene-carboxylic acid peroxyesters and mixtures thereof.

38. The method of claim 30 , wherein the photoinitiator comprises a weight percentage of the uncured radiation-curable medium ranging from 0.1% to 10%.

39. The method of claim 30 , wherein the photoinitiator comprises a weight percentage of the uncured radiation-curable medium ranging from 2 to 6%.

40. The method of claim 30 , wherein the uncured radiation-curable medium includes a moisture cure catalyst.

41. A method for curing an adhesive, comprising:

disposing in contact with an interior surface of a plastic or rubber object an adhesive composition comprising 1) an uncured radiation-curable medium comprising a UV-curable silicone, wherein the UV-curable silicone includes at least one of includes at least one of carboxylate, maleate, cinnamate, trimethylsilyl, dimethylsilyl, phenyldimethylsilyl, vinyldimethylsilyl, trifluoropropyldimethylsilyl, (4-vinylphenyl)dimethylsilyl, (vinylbenzyl)dimethylsilyl, and (vinylphenethyl)dimethylsilyl, 2) an energy modulation agent, and 3) a photo-activated photoinitiator;

applying energy from at least one of x-rays, gamma rays, or an electron beam through the plastic or rubber structure into the composition, wherein the energy interacts with the energy modulation agent and internally generates light inside the uncured radiation-curable medium at the interior surface of the plastic or rubber object and

activating the photoinitiator in the radiation-curable medium with the internally generated light and thereby curing or sterilizing the radiation-curable medium.

42. The method of claim 41 , wherein the object comprises a medical device.

43. The method of claim 41 , wherein disposing comprises disposing at least one of a telluride, a selenide, and an oxide semiconductor as the energy modulation agent.

44. The method of claim 41 , wherein the disposing comprises disposing at least one of Y 2 O 3 ; ZnSe; Mn, Er ZnSe; Mn; Mn, Yb ZnSe; Mn, Y 2 O 3 :Tb 3+ ; Y 2 O 3 :Tb 3+ , Er 3+ ; CdSe, Y 2 O 3 :Eu 3+ , Y 2 O 3 :Eu 3+ ; BaFBr:Tb 3+ ; and YF 3 :Tb 3+ as the energy modulation agent.

45. The method of claim 41 , wherein the activating comprises: activating the photoinitiator with 200-280 nm wavelength ultraviolet light.

46. The method of claim 41 , wherein the activating comprises: activating the photoinitiator with 280-320 nm wavelength ultraviolet light.

47. The method of claim 41 , wherein the activating comprises: activating the photoinitiator with 320-400 nm wavelength ultraviolet light.

48. The method of claim 41 , wherein the activating comprises: activating the photoinitiator with 350-400 nm wavelength ultraviolet light.

49. The method of claim 41 , wherein the UV-curable silicone comprises an organopolysiloxane.

50. The method of claim 41 , wherein the UV-curable silicone includes a methacrylate group.

51. The method of claim 41 , wherein the UV-curable silicone includes an acryloxy group.

52. The method of claim 41 , wherein the UV-curable silicone includes at least one of carboxylate, maleate, and cinnamate.

53. The method of claim 41 , wherein the UV-curable silicone includes at least one of trimethylsilyl, dimethylsilyl, phenyldimethylsilyl, vinyldimethylsilyl, trifluoropropyldimethylsilyl, (4-vinylphenyl)dimethylsilyl, (vinylbenzyl)dimethylsilyl, and (vinylphenethyl)dimethylsilyl.

54. The method of claim 41 , wherein the photoinitiator comprises at least one of at least one of benzoin, substituted benzoins, Michler's ketone, dialkoxyacetophenones, diethoxyacetophenone, benzophenone, substituted benzophenones, acetophenone, substituted acetophenones, xanthone, substituted xanthones, diethoxyxanthone, chloro-thio-xanthone, azo-bisisobutyronitrile, N-methyl diethanolaminebenzophenone, camphoquinone, peroxyester initiators, non-fluorene-carboxylic acid peroxyesters and mixtures thereof.

55. The method of claim 41 , wherein the photoinitiator comprises a weight percentage of the uncured radiation-curable medium ranging from 0.1% to 10%.

56. The method of claim 41 , wherein the photoinitiator comprises a weight percentage of the uncured radiation-curable medium ranging from 2 to 6%.

57. The method of claim 41 , wherein the uncured radiation-curable medium includes a moisture cure catalyst.

Continuity (7)
Division 14635677 · Mar 2, 2015
Continuation 14157039 · Jan 16, 2014
Continuation 13713974 · Dec 13, 2012
Continuation 12401478 · Mar 10, 2009
Provisional Application 61080140 · Jul 11, 2008
Provisional Application 61035559 · Mar 11, 2008
Related Publication 20150290614A1 · Oct 15, 2015
Cited By (8)
US 12,186,553 US 12,245,355 US 12,311,168 US 12,403,306 US 12,551,698 US 12,616,848 US 12,649,056 US 12,702,861