Pharmaceutical compositions comprising DGLA and use of same
The present disclosure provides orally deliverable pharmaceutical compositions comprising DGLA and to methods of using same to treat a variety of conditions and disorders.
1. A pharmaceutical composition comprising dihomo gamma linolenic acid, eicosatetraenoic acid, eicosatrienoic acid, oleic acid, linoleic acid and eicosadienoic acid encapsulated in a capsule shell wherein the composition comprises at least about 80% dihomo gamma linolenic acid by weight of total fatty acids.
2. The pharmaceutical composition of claim 1 , wherein the capsule shell comprises gelatin and glycerol.
3. The pharmaceutical composition of claim 1 , wherein up to about 1 g of dihomo gamma linolenic acid is encapsulated in the capsule shell.
4. The pharmaceutical composition of claim 1 , wherein about 200 mg to about 1 g of dihomo gamma linolenic acid is encapsulated in the capsule shell.
5. The pharmaceutical composition of claim 1 , wherein the capsule shell comprises lime bone gelatin and the capsule shell further comprises one or more of: glycerol, purified water, titanium dioxide, medium chain triglycerides and/or lecithin.
6. The pharmaceutical composition of claim 1 , comprising about 200 mg to about 1 g of dihomo gamma linolenic acid and wherein the composition comprises not more than 5% of any individual fatty acid other than dihomo gamma linolenic acid by weight of total fatty acids.