IP Library Granted Patent US 10,029,418
Granted Patent B2
US 10,029,418 · App. 14/736,952 · Granted Jul 24, 2018

Living body tissue three-dimensional model and production method therefor

Inventor: Hiroshi Misawa (Kanagawa, JP)
Assignee: TERUMO KABUSHIKI KAISHA
B29C67/0088A61B6/032A61B6/504B29C64/135B29C64/386G09B23/30A61B2017/00716A61B2034/105B29L2031/753
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Quick Facts
Patent No.
US 10,029,418
App. No.
14/736,952
Granted
Jul 24, 2018
Kind
B2
Abstract

An internal tissue including a lesion region in the human body is modeled as a three-dimensional model. By reconstructing thickness or flexibility of a lumen wall portion including the lesion region and making it possible to confirm a motion of the lumen wall or a flow of fluid in the inside of the lumen wall, a state of the lesion region in the lumen can be confirmed clearly by visual inspection or the like. As a result, the diagnosis in the lumen can be made easier.

Claims (14)

1. A method for producing a living body tissue three-dimensional model comprising:

lamination shaping the living body tissue three-dimensional model using the lesion region tomographic data produced based on three-dimensional data of a lesion region of a living body tissue in which a thickness of a lumen wall portion of a lumen portion including the lesion region is reconstructed; and

implanting a plurality of cantilever flow indicating elements into a wall of the living body tissue three-dimensional model;

wherein the cantilever flow indicating elements are small pieces each in the form of a thin plate formed in a projecting manner from the wall and each comprising a flexible leg portion and a flow abutting portion, the flexible leg portion having one end implanted into the wall, the flow abutting portion being formed at an other end of the flexible leg portion, a width of the flow abutting portion being greater than a width of the flexible leg portion.

2. The method according to claim 1 , further comprising coupling three-dimensional data with the lesion region tomographic data to form a penetrating portion of an operation instrument into a lesion region which has been reconstructed on a side face or an end face of the lumen portion.

3. The method according to claim 1 , further comprising coupling three-dimensional data of an overlapping coupling portion with the lesion region tomographic data so that no offset is provided on a lumen inside face region in a state in which a coupling portion of the lumen for coupling the adjacent parts to each other is coupled.

4. The method according to claim 1 , further comprising shaping the three-dimensional model using active energy-curing resin based on the tomographic image data of the living body.

5. A method for producing a living body tissue three-dimensional model comprising:

hardening, using tomographic image data of a living body, at least a portion of an active liquid-state energy-curing resin to shape and form a three-dimensional model of the living body tissue based on the tomographic image data of the living body; and

implanting a plurality of cantilever flow indicating elements into a wall of the three-dimensional model of the living body;

the hardening of the at least a portion of the active liquid-state energy-curing resin being performed so that the three-dimensional model of the living body tissue comprises a liquid-state compartment in which a portion of the active liquid-state energy-curing resin remains unhardened and is surrounded by the hardened resin;

wherein the cantilever flow indicating elements are small pieces each in the form of a thin plate formed in a projecting manner from the wall and each comprising a flexible leg portion and a flow abutting portion, the flexible leg portion having one end implanted into the wall, the flow abutting portion being formed at an other end of the flexible leg portion, a width of the flow abutting portion being greater than a width of the flexible leg portion.

6. The method according to claim 5 , further comprising coupling three-dimensional data with the tomographic image data to form a penetrating portion of an operation instrument into a region which has been reconstructed on a side face or an end face of a lumen portion.

7. The method according to claim 5 , further comprising coupling three-dimensional data of an overlapping coupling portion with the tomographic image data so that no offset is provided on a lumen inside face region in a state in which a coupling portion of a lumen for coupling the adjacent parts to each other is coupled.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 11, 2015
From: MISAWA, HIROSHI
To: TERUMO CORPORATION
Reel/Frame 035824/0580 →
Priority Claims (4)
JP 2008-086398 · Mar 28, 2008 · national
JP 2008-086399 · Mar 28, 2008 · national
JP 2008-086400 · Mar 28, 2008 · national
JP 2008-086401 · Mar 28, 2008 · national
Continuity (3)
Division 12891318 · Sep 27, 2010
Continuation PCTJP2009056912 · Mar 27, 2009
Related Publication 20150343710A1 · Dec 3, 2015
Cited By (1)
US 12,488,705