Phenylacetylenes
Disclosed herein are host or receptor compounds that bind targets of interest. In one embodiment the compounds bind ions, such as metal ions. A compound, or a protonate or salt thereof, having the formula of: Formula IIa wherein R 6 is an aminoalkoxy, alkylamino, nitro or —NH 2 ; n is 1 or 2; each R 2 is independently selected from an optionally substituted alkyl, halogen, optionally substituted alkoxy, optionally substituted carboxyl, or amide; a is 0 to 4.
1. A compound, or a protonate or salt thereof, having the formula of:
wherein R 6 is an aminoalkoxy, alkylamino, nitro or —NH 2 ;
each R 2 is independently selected from an optionally substituted alkyl, halogen, optionally substituted alkoxy, optionally substituted carboxyl, or amide; and
a is 0 to 4.
2. The compound of claim 1 , wherein R 6 is —O(CH 2 ) d NR 11 R 12 , wherein d is 1 to 10; and each R 11 and R 12 is independently H or lower alkyl.
3. The compound of claim 2 , wherein each of R 11 and R 12 is methyl, ethyl, n-propyl, isopropyl, n-butyl, isobutyl, or tert-butyl.
4. The compound of claim 2 , wherein each of R 11 and R 12 is H.
5. The compound of claim 2 , wherein each of R 11 and R 12 is methyl.
6. The compound of claim 2 , wherein d is 2.
7. The compound of claim 1 , wherein a is 0.
8. The compound of claim 1 , wherein R 2 is methyl, ethyl, n-propyl, isopropyl, n-butyl, isobutyl, or tert-butyl.