Granted Patent
B2
US 9,956,226 · App. 14/767,102 · Granted May 1, 2018
Methods and compounds for the inhibition of cellular proliferation
Inventors:
Gerhard Wagner (Chestnut Hill, MA); Ricard A. Rodriguez-Mias (Seattle, WA); Patrick R. Hagner (Somerville, MA)
Assignee:
President and Fellows of Harvard College
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Abstract
Methods for inhibiting translation, treating a cellular proliferative disorder, and inhibiting proliferation of cells using the compounds disclosed herein are provided.
Claims (4)
1. A method of inhibiting translation in a human or non-human mammal comprising administering to the human or non-human mammal a compound of Formula
or a pharmaceutically acceptable salt thereof.
2. The method of claim 1 wherein the compound is administered by inhalation, transdermally, orally, rectally, transmucosally, intestinally, parenterally, intramuscularly, subcutaneously or intravenously.
3. The method of claim 1 , wherein the compound is administered with a therapeutic agent.
Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Sep 7, 2016
From: HAGNER, PATRICK R.; RODRIGUEZ-MIAS, RICARD A.; WAGNER, GERHARD
To: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
Reel/Frame 039661/0650 →
CONFIRMATORY LICENSE
Recorded Aug 19, 2015
From: HARVARD UNIVERSITY
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 036389/0904 →
Continuity (2)
Provisional Application
61763017
· Feb 11, 2013