Method and system of utilizing ECG signal for central venous catheter tip positioning
Disclosed herein are a method and a medical system for utilizing of a intravascular ECG signal for central venous catheter placement. The medical system is capable of detecting the position of a catheter tip and assessing its location relative to the cavoatrial junction. The detection and assessment are performed by a multiscale analysis of the complexity of the intravascular signal data points.
1. A method of utilizing an electrocardiogram (ECG) signal for positioning a tip of a central venous catheter (CVC) comprising:
receiving signal data;
determining at least one proximity index (PxI) parameter, wherein the PxI parameter is a chaos theory complexity parameter associated with variability of the signal data; and
providing an output indicative of proximity of the CVC tip to a cavoatrial junction.
2. The method of claim 1 , wherein the signal data is intravascular ECG (ivECG) signal data.
3. The method of claim 1 , further comprising comparing the at least one PxI parameter with a proximity threshold of the CVC tip to the cavoatrial junction before providing the output.
4. The method of claim 1 , wherein the at least one PxI parameter is a density of tail distribution.
5. The method of claim 4 , wherein the tail distribution is a probability that a random variable X takes on a value more than x.
6. The method of claim 5 , wherein the random variable X belongs to a time series of differences of successive points {d 1 , d 2 , d 3 , . . . , d i , d i+1 , . . . d n−1 } where d i is an absolute difference, |v i+1 −v i | between successive points v i+1 and v i of the signal data.
7. The method of claim 6 wherein the x is variable from 0 to maximal value d i from a time series {d 1 , d 2 , d 3 , . . . , d i , d i+1 , . . . d n−1 }.
8. A method of positioning an endovascular device in vasculature, comprising:
advancing an endovascular device into the vasculature, the endovascular device having an electrode for receiving intravascular ECG (ivECG) signal data;
receiving ivECG signal data using the electrode;
determining at least one proximity index (PxI) parameter based on the received ivECG signal data; and
providing an output indicative of proximity of the endovascular device to a part of a patient's body after determining the at least one PxI parameter.
9. The method of claim 8 , further comprising comparing the at least one PxI parameter with a proximity threshold indicating a location of the endovascular device in relation to a part of the patient's body before providing the output.
10. The method of claim 8 , wherein the endovascular device is a central venous catheter having a tip, and advancing the endovascular device into the vasculature includes advancing the central venous catheter into the vasculature, the central venous catheter having the electrode for receiving ivECG signal data.
11. The method of claim 10 , wherein providing an output includes providing an output indicative of proximity of the tip of the central venous catheter to a cavoatrial junction of the patient's body.
12. The method of claim 9 , wherein the determining at least one PxI parameter based on the received ivECG signal data and the comparing the at least one PxI parameter with a proximity threshold are done using a multiscale complexity analysis module including software programmed for processing the ivECG signal data.
13. The method of claim 8 , wherein the at least one PxI parameter is a density of tail distribution.
14. The method of claim 13 , wherein the tail distribution is a probability that a random variable X takes on a value more than x.
15. The method of claim 14 , wherein the random variable X belongs to a time series of differences of successive points {d 1 , d 2 , d 3 , . . . , d i , d i+1 , . . . d n−1 } where d i is an absolute difference, |v i+1 −v i between successive points v i+1 and v i of the ivECG signal data.
16. The method of claim 15 wherein the x is variable from 0 to maximal value d i from the time series {d 1 , d 2 , d 3 , . . . , d i , d i+1 , . . . d n−1 }.
17. The method of claim 8 , wherein the output indicative of proximity of the endovascular device to the part of the patient's body is graphical output shown on a display.
18. A medical system for placement of an endovascular device comprising:
a placement unit including an electrode for acquiring intravascular ECG (ivECG) signal data;
a multiscale complexity analysis module including software programmed for processing the ivECG signal data acquired by the electrode; and
an audio and/or visual device configured to provide an audio and/or visual indication of proximity index (PxI) and/or a proximity of the endovascular device to a part of a patient's body.
19. The medical system of claim 18 , wherein the endovascular device is a central venous catheter and the part of the patient's body is a cavoatrial junction of the patient's body.
20. The medical system of claim 18 , wherein the software of the multiscale complexity analysis module is programmed to determine at least one PxI value based on the ivECG signal data acquired by the electrode.
21. The medical system of claim 20 , wherein the audio and/or visualization device is configured to provide a user with an audio and/or visual indication of PxI and/or the proximity of the endovascular device to the part of the patient's body based on a comparison of the at least one PxI value with the proximity threshold.