Granted Patent
B2
US 10,295,547 · App. 14/775,278 · Granted May 21, 2019
Use and treatment of di-amino acid repeat-containing proteins associated with ALS
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Abstract
Disclosed herein are methods and compositions for identifying and/or treating subjects having or likely to have amyotrophic lateral sclerosis (ALS) or frontotemporal dementia (FTD). Antibodies specific for one or more di-amino acid repeat-containing proteins are also provided herein.
Claims (3)
1. A method of producing an antibody, the method comprising administering to a subject a poly-(Pro-Arg) di-amino acid repeat-containing protein.
2. The method of claim 1 , wherein the poly-(Pro-Arg) di-amino acid repeat-containing protein comprises the sequence set forth in SEQ ID NO: 19.
3. The method of claim 1 , further comprising the step of isolating the antibody from the subject.
Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Nov 4, 2015
From: RANUM, LAURA; ZU, TAO
To: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED
Reel/Frame 036953/0708 →
Continuity (3)
Provisional Application
61883219
· Sep 27, 2013
Provisional Application
61786258
· Mar 14, 2013