Granted Patent
B2
US 9,630,906 · App. 14/780,845 · Granted Apr 25, 2017
Amine salts of pitavastatin and rosuvastatin
Inventors:
Ben De Lange (Echt, NL); Henricus Leonardus Marie Elsenberg (Echt, NL); Karin Henderika Maria Bessembinder (Echt, NL)
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Abstract
The present invention relates to unsaturated amine salts of HMG-CoA reductase inhibitors, to a method of producing said amine salts and to the use of said amine salts in the production of pharmaceutically acceptable salts of HMG-CoA reductase inhibitors.
Claims (2)
1. An amine salt of pitavastatin or rosuvastatin, wherein the amine is selected from the group consisting of 2-furfuryl amine, 3-furfuryl amine and propargyl amine.
2. The amine salt of claim 1 , which is the 2-furfuryl amine salt of rosuvastatin.
Assignments (2)
CHANGE OF NAME
Recorded Apr 2, 2019
From: DSM SINOCHEM PHARMACEUTICALS NETHERLANDS B.V.
To: CENTRIENT PHARMACEUTICALS NETHERLANDS B.V.
Reel/Frame 048775/0029 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Nov 25, 2015
From: DE LANGE, BEN; ELSENBERG, HENRICUS LEONARDUS MARIE; BESSEMBINDER, KARIN HENDERIKA MARIA
To: DSM SINOCHEM PHARMACEUTICALS NETHERLANDS B.V.
Reel/Frame 037141/0541 →
Priority Claims (2)
EP 13161843
· Mar 29, 2013
· regional
EP 13182231
· Aug 29, 2013
· regional
Continuity (1)