Granted Patent
B2
US 11,293,870 · App. 14/780,927 · Granted Apr 5, 2022
Vital stain
Inventors:
Akira Mizoguchi (Mia, JP); Takeshi Fujiwara (Mie, JP); Koji Tanaka (Mie, JP); Shujie Wang (Mie, JP); Kousyoku Sai (Mie, JP); Kazushi Kimura (Mie, JP)
Assignee:
MIE UNIVERSITY
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Abstract
A vital stain for observation under multiphoton laser microscopy, the vital stain comprising one or more edible dye compounds.
Claims (4)
1. An in vivo method of detecting cancer cells, using a stain, the method of detecting cancer cells comprising:
1) applying the stain to the cells in vivo, and
2) distinguishing normal cells and cancer cells based on a difference in cell staining intensity, using a multiphoton laser microscope,
wherein said stain specifically stains cancer cells in contrast to normal cells, and wherein the stain comprises curcumin.
Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Sep 4, 2026
From: MIE UNIVERSITY
To: LASER BENEFIT LLC
Reel/Frame 075918/0254 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Sep 28, 2015
From: MIZOGUCHI, AKIRA; FUJIWARA, TAKESHI; TANAKA, KOJI; WANG, SHUJIE; SAI, KOUSYOKU; KIMURA, KAZUSHI
To: MIE UNIVERSITY
Reel/Frame 036673/0232 →
Priority Claims (3)
JP JP2013-074953
· Mar 29, 2013
· national
JP JP2013-075150
· Mar 29, 2013
· national
JP JP2013-075256
· Mar 29, 2013
· national
Continuity (1)