Reducing risk of contracting clostridium-difficile associated disease
View Patent ↗A method of treating a patient to reduce risk of developing Clostridium difficile -associated disease or reducing existing Clostridium difficile -associated disease in a mammalian subject involves administering to a mammalian subject an effective amount of a germination-inhibiting compound derived from taurocholate. Novel compounds of this class are also provided.
1. A method of treating Clostridium difficile -associated disease in a subject that has been diagnosed with Clostridium difficile -associated disease prior to treatment, the method comprising administering to a mammalian subject a therapeutically effective amount of a compound having a structure represented by a formula:
or a pharmaceutically acceptable salt thereof.
2. The method of claim 1 , wherein the subject is concurrently receiving antibiotic therapy.
3. The method of claim 1 , wherein the subject is human.
4. The method of claim 1 , wherein the subject is a farm animal.