IP Library Granted Patent US 10,105,476
Granted Patent B2
US 10,105,476 · App. 14/808,827 · Granted Oct 23, 2018

Fluid purification system

Inventors: Richard B. Peterson (Corvallis, OR); James R. Curtis (Portland, OR)
Assignees: Oregon State University; Outset Medical, Inc.
A61M1/1686A61M1/1658A61M1/1672B01D61/08B01D61/18B01D61/30B01D61/58C02F1/001C02F1/02C02F1/20C02F1/283C02F1/441C02F1/444C02F9/005F24H1/121A61M2205/75B01D61/025B01D61/145B01D2311/04B01D2311/06B01D2311/25C02F2103/026C02F2209/005C02F2209/006C02F2209/03C02F2301/043C02F2301/046C02F2303/04
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Quick Facts
Patent No.
US 10,105,476
App. No.
14/808,827
Granted
Oct 23, 2018
Kind
B2
Abstract

Certain disclosed embodiments concern systems and methods of preparing dialysate for use in a home dialysis system that is compact and light-weight relative to existing systems and consumes relatively low amounts of energy. The method includes coupling a household water stream to a dialysis system; filtering the water stream; heating the water stream to at least about 138 degrees Celsius in a non-batch process to produce a heated water stream; maintaining the heated water stream at or above at least about 138 degrees Celsius for at least about two seconds; cooling the heated water stream to produce a cooled water stream; ultrafiltering the cooled water stream; and mixing dialysate components into the cooled water stream in a non-batch process.

Claims (12)

1. A method of preparing dialysate for use in a dialysis system, comprising:

flowing an inlet stream of household water into an inflow microchannel of a microfluidic heat exchanger;

heating the inlet water stream to at least 138° C. within the microfluidic heat exchanger in a non-batch process to produce a heated water stream;

maintaining the heated water stream at or above at least 138° C. for at least two seconds;

flowing the heated water stream in an outflow microchannel of the microfluidic heat exchanger;

cooling the heated water stream, and heating the inlet water stream, by transferring heat from the heated water stream in the outflow microchannel to the inlet water stream in the inflow microchannel to produce a cooled water stream at an outlet of the heat exchanger;

ultrafiltering the cooled water stream; and

mixing dialysate components into the cooled water stream in a non-batch process.

2. The method of claim 1 wherein the step of flowing an inlet stream comprises pumping the household water into the inflow microchannel.

3. The method of claim 1 further comprising maintaining the water at least at a saturation pressure such that the water does not change state during the method.

4. The method of claim 3 wherein the step of maintaining the water at a saturation pressure comprises using a pump to increase water pressure to a pressure higher than the saturation pressure of the heated water stream.

5. The method of claim 3 wherein the step of maintaining the water at a saturation pressure comprises passing the cooled water stream through a flow restrictor.

Assignments (12)
SECURITY INTEREST Recorded Jan 15, 2025
From: OUTSET MEDICAL, INC.
To: PERCEPTIVE CREDIT HOLDINGS IV, LP
Reel/Frame 069880/0739 →
RELEASE OF SECURITY INTEREST Recorded Jan 9, 2025
From: SLR INVESTMENT CORP., AS AGENT
To: OUTSET MEDICAL, INC.
Reel/Frame 069858/0267 →
RELEASE OF SECURITY INTEREST Recorded Jan 9, 2025
From: GEMINO HEALTHCARE FINANCE, LLC
To: OUTSET MEDICAL, INC.
Reel/Frame 069800/0767 →
SECURITY INTEREST Recorded Nov 4, 2022
From: OUTSET MEDICAL, INC.
To: GEMINO HEALTHCARE FINANCE, LLC
Reel/Frame 061654/0556 →
INTELLECTUAL PROPERTY SECURITY AGREEMENT Recorded Nov 3, 2022
From: OUTSET MEDICAL, INC.
To: SLR INVESTMENT CORP., AS AGENT
Reel/Frame 061879/0764 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 15, 2021
From: OREGON STATE UNIVERSITY
To: OUTSET MEDICAL, INC.
Reel/Frame 058112/0875 →
RELEASE OF SECURITY INTEREST Recorded Jul 3, 2020
From: PERCEPTIVE CREDIT HOLDINGS, LP, AS COLLATERAL AGENT
To: OUTSET MEDICAL, INC.
Reel/Frame 053115/0307 →
PATENT SECURITY AGREEMENT Recorded Jun 30, 2017
From: OUTSET MEDICAL, INC.
To: PERCEPTIVE CREDIT HOLDINGS, LP
Reel/Frame 043070/0791 →
CHANGE OF NAME Recorded Aug 4, 2015
From: HOME DIALYSIS PLUS, LTD.
To: OUTSET MEDICAL, INC.
Reel/Frame 036263/0813 →
CHANGE OF NAME Recorded Aug 4, 2015
From: STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF OREGON STATE UNIVERSITY
To: OREGON STATE UNIVERSITY
Reel/Frame 036263/0809 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 4, 2015
From: CURTIS, JAMES R.
To: HOME DIALYSIS PLUS, LTD.
Reel/Frame 036245/0698 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 4, 2015
From: PETERSON, RICHARD B.; WANG, HAILEI; INGRAM-GOBLE, ROBBIE; FISHER, LUKE W.; GARRISON, ANNA E.
To: STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF OREGON STATE UNIVERSITY
Reel/Frame 036245/0668 →
Continuity (4)
Continuation 13965720 · Aug 13, 2013
Continuation 13068038 · Apr 29, 2011
Continuation 12795382 · Jun 7, 2010
Related Publication 20150328386A1 · Nov 19, 2015
Cited By (3)
US 12,201,762 US 12,390,565 US 12,465,671