Thermal modulation of an inhalable medicament
A thermally modulating inhalable medicament delivery device may deliver an inhalable medicament as an aerosol, vapor, or partial aerosol and partial vapor mixture. The inhalable medicament may be delivered to a target in a subject. Described herein are devices, systems, and methods for delivering an inhalable medicament to a subject.
1. A method for delivering an inhalable medicament, comprising:
coupling a cartridge to a housing with a reservoir tap having a hollow interior, the cartridge comprising:
a penetrable seal positioned adjacent to the reservoir tap when the cartridge is coupled to the housing; and
an inhalable medicament within the cartridge that is compressed to a pressure above ambient pressure; and
penetrating said penetrable seal with the reservoir tap, aerosolizing the inhalable medicament and ejecting said inhalable medicament into the housing.
2. The method of claim 1 , wherein penetrating the penetrable seal comprises penetrating a self-sealing penetrable seal.
3. The method of claim 1 , further comprising:
heating the inhalable medicament.
4. The method of claim 3 , wherein heating the inhalable medicament comprises heating the inhalable medicament within the housing.
5. The method of claim 1 , wherein penetrating the penetrable seal comprises sliding the reservoir tap within the housing.
6. The method of claim 1 , further comprising:
creating communication between the cartridge and the hollow interior of the reservoir tap with a port of the reservoir tap when penetrating the penetrable seal with the reservoir tap.
7. The method of claim 1 , wherein coupling the cartridge to the housing comprises coupling a cartridge including the inhalable medicament substantially in liquid form to the housing.
8. A method for delivering an inhalable medicament with an orientation-independent system, comprising:
penetrating a seal of a cartridge to enable communication of an inhalable medicament at an above-ambient pressure from a medicament reservoir of the cartridge, positioned adjacent to the seal, to a housing of a device capable of delivering the inhalable medicament; and
releasing the inhalable medicament from the medicament reservoir upon establishing communication between the medicament reservoir and the housing.
9. The method of claim 8 , wherein penetrating the seal comprises penetrating a self-sealing seal.
10. The method of claim 8 , further comprising:
coupling the cartridge to the housing of the device capable of delivering the inhalable medicament, wherein penetrating the seal comprises penetrating the seal with a reservoir tap of the device.
11. The method of claim 10 , wherein penetrating the seal comprises sliding the reservoir tap into the seal.
12. The method of claim 11 , wherein releasing the inhalable medicament occurs upon penetrating the seal.
13. The method of claim 12 , further comprising:
heating the medicament within the housing of the device capable of delivering the inhalable medicament.