IP Library › Patent Application 14877655
Patent Application
App. No. 14/877,655

LOX AND LOXL2 INHIBITORS AND USES THEREOF

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Quick Facts
Patent No.
US None
App. No.
14/877,655
Abstract

The present application relates to anti-LOX and anti-LOXL2 antibodies and their use in purification, diagnostic and therapeutic methods. Antibodies include monoclonal antibodies, humanized antibodies and functional fragments thereof. Anti-LOX and anti-LOXL2 antibodies can be used to identify and treat conditions such as a fibrotic condition, angiogenesis, or to prevent a transition from an epithelial cell state to a mesenchymal cell state.

Claims (1)

1 . An isolated antibody or antigen binding fragment thereof, that specifically binds to an epitope having an amino acid sequence set forth as SEQ ID NO: 6.

Assignments (2)
MERGER Recorded Feb 18, 2016
From: ARRESTO BIOSCIENCES, INC.
To: GILEAD BIOLOGICS, INC.
Reel/Frame 037770/0674 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 18, 2016
From: SMITH, VICTORIA; OGG, SCOTT; VAN VLASSELAER, PETER; BARRY, VIVIAN E.; MARSHALL, DEREK; HOLZER, ALISON KAY; RODRIGUEZ, HECTOR; OYASU, MIHO; MCCAULEY, SCOTT ALAN; GARCIA, CARLOS AURELIO; BIERMANN, DONNA HIROKO TOKUOKA
To: ARRESTO BIOSCIENCES, INC.
Reel/Frame 037770/0682 →