Advanced endovascular clip and method of using same
Embodiments disclosed herein are directed towards an endovascular clip comprising a proximal anchoring member and a distal self-expanding member. The proximal anchoring member and distal self-expanding member are configured to extend across opposite sides of a neck of an aneurysm.
1. An endovascular clip comprising:
means for anchoring the endovascular clip on a vessel lumen side of an aneurysm, said means comprising at least two anchoring components; and
a distal self-expanding member;
wherein the distal self-expanding member comprises a mesh;
wherein the means for anchoring and distal self-expanding member comprise self-expanding material configured to have an original configuration and a deformed configuration;
wherein said means for anchoring and said distal self-expanding member are configured to extend across opposite sides of a neck of an aneurysm;
a proximal detachable hypotube detachably coupled to the means for anchoring; and
a distal detachable wire detachably coupled to the distal self-expanding member;
wherein the distal detachable wire and proximal detachable hypotube are in a concentric configuration, and
wherein the means for anchoring is disposed proximal to the distal self-expanding member with respect to the hypotube,
wherein the distal detachable wire comprises a manually-adjustable steering joint, and
wherein the means for anchoring and distal self-expanding member are independently detachable and separately maneuverable.
2. The endovascular clip of claim 1 , wherein the distal detachable wire further comprises a locking mechanism.
3. The endovascular clip of claim 1 , wherein the distal detachable wire further comprises a detaching joint detachably coupling distal and proximal portions of the distal detachable wire.
4. The endovascular clip of claim 2 or 3 , wherein the means for anchoring further comprises a proximal detachment zone.
5. The endovascular clip of claim 4 , wherein the means for anchoring activates the locking mechanism.
6. The endovascular clip of claim 4 , wherein the means for anchoring activates the detaching of the detaching joint.
7. The endovascular clip of claim 4 , wherein the means for anchoring activates the detaching of the proximal detachable hypotube at the proximal detachment zone.
8. The endovascular clip of claim 1 , wherein the distal self-expanding member original configuration is a conical shape.
9. The endovascular clip of claim 1 , wherein the distal self-expanding member original configuration is a planar shape.
10. The endovascular clip of claim 1 , wherein the distal self-expanding member comprises a manually-adjustable shape.
11. The endovascular clip of claim 1 , wherein the means for anchoring anchoring components are manually-adjustable.
12. The endovascular clip of claim 1 , wherein the mesh further comprises a bioactive material configured to promote cell growth.
13. The endovascular clip of claim 12 , wherein said bioactive material comprises a thrombogenic material selected from the group consisting of collagen, fibrinogen, vitronectin, other plasma proteins, growth factors, peptides of said growth factors having attached RGD (arginine glycine-aspartic acid) residues, phospholipids, polymers with phosphorylcholine functionality, and any combination thereof.
14. The endovascular clip of claim 12 , wherein said bioactive material comprises stem cells.
15. An endovascular clip comprising:
means for anchoring the endovascular clip on a vessel lumen side of an aneurysm, said means comprising at least two anchoring components; and
a distal self-expanding member;
wherein the distal self-expanding member comprises a mesh;
wherein the means for anchoring and distal self-expanding member comprise self-expanding material configured to have an original configuration and a deformed configuration;
wherein said means for anchoring and said distal self-expanding member are configured to extend across opposite sides of a neck of an aneurysm; and
a distal detachable wire detachably coupled to the distal self-expanding member;
wherein the distal detachable wire comprises a manually-adjustable steering joint, and
wherein the means for anchoring is disposed proximal to the distal self-expanding member with respect to a hypotube detachably coupled to the means for anchoring.