IP Library Granted Patent US 9,717,722
Granted Patent B2
US 9,717,722 · App. 14/890,696 · Granted Aug 1, 2017

Methods and agents for treating tyrosinase-positive albinism

Inventors: Seth J. Orlow (New York, NY); Prashiela Manga (Forest Hills, NY)
Assignee: New York University
A61K31/4706A61K31/122A61K31/436
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Quick Facts
Patent No.
US 9,717,722
App. No.
14/890,696
Granted
Aug 1, 2017
Kind
B2
Abstract

Methods for treating a subject with tyrosinase-positive albinism; agents and compositions thereof for use in treating tyrosinase-positive albinism; and medicaments for treating tyrosinase-positive albinism are described herein. Such methods; agents and compositions thereof; and medicaments relate to chloroquine or rapamycin or compositions thereof and may further relate to nitisinone used in conjunction with the chloroquine or rapamycin or a composition of either of which.

Claims (5)

1. A method for treating tyrosinase-positive albinism in a subject, the method comprising administering a therapeutically effective amount of chloroquine or a composition thereof to the subject.

2. The method of claim 1 , further comprising administering a therapeutically effective amount of nitisinone to the subject.

3. The method of claim 1 , wherein the subject is a mammal.

4. The method of claim 3 , wherein the mammal is a human.

5. The method of claim 1 , wherein the administering is systemic or topical.

Assignments (2)
CONFIRMATORY LICENSE Recorded Apr 16, 2018
From: NEW YORK UNIVERSITY
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 045547/0744 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 6, 2016
From: ORLOW, SETH J.; MANGA, PRASHIELA
To: NEW YORK UNIVERSITY
Reel/Frame 038815/0032 →
Continuity (2)
Provisional Application 61822519 · May 13, 2013
Related Publication 20160120860A1 · May 5, 2016