Topical neurological stimulation
A topical nerve stimulator patch and system are provided comprising a dermal patch; an electrical signal generator associated with the patch; a signal receiver to activate the electrical signal generator; a power source for the electrical signal generator associated with the patch; an electrical signal activation device; and a nerve feedback sensor.
1. A topical nerve stimulation system patch comprising:
a flexible substrate;
a malleable dermis conforming bottom surface of the substrate comprising adhesive and adapted to contact the dermis;
a flexible top outer surface of the substrate approximately parallel to the bottom surface;
one or more electrodes positioned on the patch proximal to the bottom surface and located beneath the top outer surface and directly contacting the flexible substrate;
electronic circuitry embedded in the patch and located beneath the top outer surface and integrated as a system on a chip that is directly contacting the flexible substrate, the electronic circuitry integrated as the system on the chip and comprising;
an electrical signal generator integral to the malleable dermis conforming bottom surface configured to electrically activate the one or more electrodes;
a signal activator coupled to the electrical signal generator; and
a nerve stimulation sensor that provides feedback in response to a stimulation of one or more nerves;
an antenna configured to communicate with a remote activation device;
a power source in electrical communication with the electrical signal generator, and the signal activator;
the signal activator configured to activate in response to receipt of a communication with the activation device by the antenna;
the electrical signal generator configured to generate one or more electrical stimuli in response to activation by the signal activator; and
the electrical stimuli configured to stimulate one or more nerves of a user wearing the nerve stimulation system patch at least at one location proximate to the patch.
2. The topical nerve stimulation patch of claim 1 , the top outer surface configured to maintain an approximately parallel relationship to the bottom surface when the patch is flexibly coupled to a curved portion of a dermis.
3. The topical nerve stimulation patch of claim 1 , further comprising a feedback sensor configured to sense muscle activation of a user in response to the nerve stimulation.
4. The topical nerve stimulation patch of claim 1 , the antenna configured to communicate muscle activation data to the remote activation device.
5. The topical nerve stimulation patch of claim 1 , the electrical signal generator configured to generate a pattern of stimulation, sensing and analyzing, and revising the pattern based on the sensing.
6. The topical nerve stimulation patch of claim 5 , the pattern initially begins with sensing and analyzing before stimulation.
7. The topical nerve stimulation patch of claim 1 , the electrodes are arranged as a plurality of concentric electrodes, and varying an amount of power from the power source at the electrodes causes a tissue depth of the stimulation to vary.
8. The topical nerve stimulation patch of claim 1 , the electrodes are arranged in a plurality of parallel strips, and the electrical stimuli can be generated parallel to or perpendicular to the patch.
9. The topical nerve stimulation patch of claim 1 , the electrodes are arranged in a matrix, and the electrical stimuli can be generated between any of two or more electrodes in the matrix.
10. The topical nerve stimulation patch of claim 1 , the electrodes are arranged as interlocked pairs of electrodes that provide beam forming in response to an application of time-varying voltages.
11. The topical nerve stimulation patch of claim 1 , the nerve stimulation sensor comprises an array of sensors that function as a phased array antenna configured to receive ultrasound signals.
12. The topical nerve stimulation patch of claim 11 , the array of sensors comprise piezoelectric sensors or micro-electro-mechanical sensors.
13. The topical nerve stimulation patch of claim 1 , the electrodes comprise adhesive conductive pads.
14. A method of using a topical nerve stimulation system patch for electrical stimulation, the method comprising:
applying the patch to a dermis using adhesive, the patch comprising:
a flexible substrate;
a malleable dermis conforming bottom surface of the substrate comprising adhesive and adapted to contact the dermis;
a flexible top outer surface of the substrate approximately parallel to the bottom surface;
one or more electrodes positioned on the patch proximal to the bottom surface and located beneath the top outer surface and coupled to the flexible substrate;
electronic circuitry embedded in the patch and located beneath the top outer surface and integrated as a system on a chip that is in direct contact with the flexible substrate, the electronic circuitry integrated as the system on the chip and comprising:
an electrical signal generator integral to the malleable dermis conforming bottom surface configured to electrically activate the one or more electrodes;
a signal activator coupled to the electrical signal generator;
a nerve stimulation sensor that provides feedback in response to a stimulation of one or more nerves;
an antenna configured to communicate with a remote activation device;
a power source in electrical communication with the electrical signal generator, and the signal activator;
the signal activator configured to activate in response to receipt of a communication with the activation device by the antenna;
the electrical stimuli configured to stimulate one or more nerves of a user wearing the nerve stimulation system patch at least at one location proximate to the patch;
generating one or more electrical stimuli in response to activation by the signal activator; and
receiving feedback from the electrical stimuli.
15. The method of claim 14 , the generating one or more electrical stimuli in response to activation by the signal activator comprises a pattern of stimulation, sensing and analyzing, and the pattern is revised based on the sensing.
16. The method of claim 15 , the pattern initially begins with sensing and analyzing before stimulation.
17. The method of claim 14 , the electrodes are arranged as a plurality of concentric electrodes, further comprising varying an amount of power from the power source at the electrodes causing a tissue depth of the stimulation to vary.
18. The method of claim 14 , the electrodes are arranged in a plurality of parallel strips, further comprising generating the electrical stimuli parallel to or perpendicular to the patch.
19. The method of claim 14 , the electrodes are arranged in a matrix, further comprising generating the electrical stimuli between any of two or more electrodes in the matrix.
20. The method of claim 14 , the electrodes are arranged as interlocked pairs of electrodes, further comprising providing beam forming in response to an application of time-varying voltages.
21. The method of claim 14 , the nerve stimulation sensor comprises an array of sensors that function as a phased array antenna configured to receive ultrasound signals.