IP Library › Granted Patent US 10,006,923
Granted Patent B2
US 10,006,923 · App. 14/897,907 · Granted Jun 26, 2018

Method for measuring glycated hemoglobin

Inventors: Noriyuki Ogawa (Shizuoka, JP); Fumi Umehara (Shiuoka, JP); Takehide Kimura (Tokyo, JP); Kousaku Murata (Kyoto, JP); Wataru Hashimoto (Kyoto, JP)
Assignees: KYOWA MEDEX CO., LTD.; KYOTO UNIVERSITY
G01N33/723C12Q1/26G01N33/725
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Quick Facts
Patent No.
US 10,006,923
App. No.
14/897,907
Granted
Jun 26, 2018
Kind
B2
Abstract

The present invention provides a method for measuring glycated hemoglobin in a sample, which comprises directly oxidizing glycated hemoglobin in a sample, and then measuring a substance produced or consumed by the oxidation; and a method for measuring glycated hemoglobin in a sample, which comprises directly oxidizing glycated hemoglobin in a sample using an enzyme, and then measuring a substance produced or consumed by the oxidation. A method for measuring glycated hemoglobin of the present invention is useful for diagnosing lifestyle-related disease such as diabetes mellitus.

Claims (6)

1. A method for measuring glycated hemoglobin in a sample, wherein the method comprises:

(i) contacting glycated hemoglobin in the sample with an enzyme that directly oxidizes glycated hemoglobin, wherein the glycated hemoglobin is not degraded by a protease; and

(ii) measuring a substance produced or consumed in step (i).

2. The method of claim 1 , wherein the produced substance is hydrogen peroxide.

3. The method of claim 1 , wherein the glycated hemoglobin is hemoglobin A1c.

4. The method of claim 2 , wherein the glycated hemoglobin is hemoglobin A1c.

Assignments (5)
CHANGE OF NAME Recorded Sep 23, 2025
From: KYOWA MEDEX CO., LTD.
To: HITACHI CHEMICAL DIAGNOSTICS SYSTEMS CO., LTD.
Reel/Frame 072925/0508 →
CHANGE OF NAME Recorded Sep 23, 2025
From: HITACHI CHEMICAL DIAGNOSTICS SYSTEMS CO., LTD.
To: MINARIS MEDICAL CO., LTD.
Reel/Frame 072925/0657 →
CHANGE OF NAME Recorded Sep 23, 2025
From: MINARIS MEDICAL CO., LTD.
To: CANON MEDICAL DIAGNOSTICS CORPORATION
Reel/Frame 072925/0690 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 1, 2016
From: MURATA, KOUSAKU; HASHIMOTO, WATARU
To: KYOTO UNIVERSITY
Reel/Frame 037863/0765 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 1, 2016
From: OGAWA, NORIYUKI; UMEHARA, FUMI; KIMURA, TAKEHIDE
To: KYOWA MEDEX CO., LTD.
Reel/Frame 037863/0833 →
Priority Claims (1)
JP 2013-143276 · Jul 9, 2013 · national
Continuity (1)
Related Publication 20160123999A1 · May 5, 2016